| Title |
The effect of hypohydration on endothelial function in young healthy adults
|
|---|---|
| Published in |
European Journal of Nutrition, February 2016
|
| DOI | 10.1007/s00394-016-1170-8 |
| Pubmed ID | |
| Authors |
Giannis Arnaoutis, Stavros A. Kavouras, Nikolaos Stratakis, Marita Likka, Asimina Mitrakou, Christos Papamichael, Labros S. Sidossis, Kimon Stamatelopoulos |
| Abstract |
Hypohydration has been suggested as a predisposing factor for several pathologies including cardiovascular diseases (CVD). While CVD are the leading cause of death worldwide, no study has investigated whether acute hypohydration affects endothelial function and cardiovascular function. Ten young, healthy males participated in this crossover study (age: 24.3 ± 2.3 year; weight: 80.8 ± 5.3 kg; BMI: 24.3 ± 0.4 kg m(-2)). Each subject completed two measurements of endothelial function by flow-mediated dilation (FMD) in euhydrated and hypohydrated state separated by 24 h. Following baseline assessment of hydration status and FMD, the subjects completed 100 min of low-intensity intermittent walking exercise to achieve hypohydration of -2 % of individual body mass. For the rest of the day, a standardized, low water content diet was provided. The following morning, hydration markers and endothelial function were recorded. Hypohydration by -1.9 ± 0.1 % of body mass resulted in decreased plasma volume by -3.5 ± 1.8 % and increased plasma osmolality by 9 ± 2 mmol kg(-1) (P < 0.001). FMD as a response to hypohydration decreased by -26.8 ± 3.9 % (P < 0.05). The data suggested that a small degree of hypohydration induced by moderate exercise and fluid restriction significantly impaired endothelial function. |
X Demographics
The data shown below were collected from the profiles of 31 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 9 | 29% |
| France | 1 | 3% |
| Iceland | 1 | 3% |
| Greece | 1 | 3% |
| Canada | 1 | 3% |
| Estonia | 1 | 3% |
| United Kingdom | 1 | 3% |
| Saudi Arabia | 1 | 3% |
| Brazil | 1 | 3% |
| Other | 0 | 0% |
| Unknown | 14 | 45% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 20 | 65% |
| Practitioners (doctors, other healthcare professionals) | 7 | 23% |
| Scientists | 4 | 13% |
Mendeley readers
The data shown below were compiled from readership statistics for 97 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Spain | 1 | 1% |
| United States | 1 | 1% |
| El Salvador | 1 | 1% |
| Unknown | 94 | 97% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 17 | 18% |
| Student > Master | 12 | 12% |
| Student > Ph. D. Student | 9 | 9% |
| Other | 7 | 7% |
| Researcher | 6 | 6% |
| Other | 21 | 22% |
| Unknown | 25 | 26% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 19 | 20% |
| Sports and Recreations | 13 | 13% |
| Nursing and Health Professions | 12 | 12% |
| Biochemistry, Genetics and Molecular Biology | 6 | 6% |
| Agricultural and Biological Sciences | 4 | 4% |
| Other | 15 | 15% |
| Unknown | 28 | 29% |
Attention Score in Context
This research output has an Altmetric Attention Score of 121. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 17 April 2024.
All research outputs
#351,830
of 25,729,842 outputs
Outputs from European Journal of Nutrition
#110
of 2,713 outputs
Outputs of similar age
#6,479
of 411,925 outputs
Outputs of similar age from European Journal of Nutrition
#3
of 52 outputs
Altmetric has tracked 25,729,842 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 98th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 2,713 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 25.7. This one has done particularly well, scoring higher than 95% of its peers.
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We're also able to compare this research output to 52 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 94% of its contemporaries.