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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Captopril analogues as metallo-β-lactamase inhibitors
|
|---|---|
| Published in |
Bioorganic & Medicinal Chemistry Letters, February 2016
|
| DOI | 10.1016/j.bmcl.2016.02.007 |
| Pubmed ID | |
| Authors |
Yusralina Yusof, Daniel T.C. Tan, Omid Khalili Arjomandi, Gerhard Schenk, Ross P. McGeary |
| Abstract |
A number of captopril analogues were synthesised and tested as inhibitors of the metallo-β-lactamase IMP-1. Structure-activity studies showed that the methyl group was unimportant for activity, and that the potencies of these inhibitors could be best improved by shortening the length of the mercaptoalkanoyl side-chain. Replacing the thiol group with a carboxylic acid led to complete loss of activity, and extending the length of the carboxylate group led to decreased potency. Good activity could be maintained by substituting the proline ring with pipecolic acid. |
X Demographics
The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| South Africa | 1 | 33% |
| Colombia | 1 | 33% |
| United Kingdom | 1 | 33% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 3 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 53 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 53 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 13 | 25% |
| Student > Ph. D. Student | 8 | 15% |
| Student > Bachelor | 7 | 13% |
| Researcher | 6 | 11% |
| Student > Doctoral Student | 3 | 6% |
| Other | 8 | 15% |
| Unknown | 8 | 15% |
| Readers by discipline | Count | As % |
|---|---|---|
| Chemistry | 19 | 36% |
| Biochemistry, Genetics and Molecular Biology | 11 | 21% |
| Pharmacology, Toxicology and Pharmaceutical Science | 4 | 8% |
| Immunology and Microbiology | 2 | 4% |
| Agricultural and Biological Sciences | 2 | 4% |
| Other | 3 | 6% |
| Unknown | 12 | 23% |
Attention Score in Context
This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 18 February 2016.
All research outputs
#16,720,137
of 25,371,288 outputs
Outputs from Bioorganic & Medicinal Chemistry Letters
#12,099
of 13,779 outputs
Outputs of similar age
#234,797
of 405,717 outputs
Outputs of similar age from Bioorganic & Medicinal Chemistry Letters
#86
of 133 outputs
Altmetric has tracked 25,371,288 research outputs across all sources so far. This one is in the 32nd percentile – i.e., 32% of other outputs scored the same or lower than it.
So far Altmetric has tracked 13,779 research outputs from this source. They receive a mean Attention Score of 4.9. This one is in the 11th percentile – i.e., 11% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 405,717 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 39th percentile – i.e., 39% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 133 others from the same source and published within six weeks on either side of this one. This one is in the 32nd percentile – i.e., 32% of its contemporaries scored the same or lower than it.