Title |
Osteoporosis Associated with Epilepsy and the Use of Anti-Epileptics—a Review
|
---|---|
Published in |
Current Osteoporosis Reports, February 2016
|
DOI | 10.1007/s11914-016-0302-7 |
Pubmed ID | |
Authors |
Sandra J. Petty, Helen Wilding, John D. Wark |
Abstract |
The increased rate of fractures associated with epilepsy has been long recognised but remains incompletely understood. Study quality and study results have varied, with some but not all studies showing bone diseases including osteoporosis and/or osteomalacia, and a high prevalence of vitamin D insufficiency and deficiency are also noted. Falls risk can also be higher in patients with epilepsy taking anti-epileptic medications, potentially leading to fracture. Larger research collaborations are recommended to further advance understanding in this field, particularly to examine underlying genetic and pharmacogenomic associations of epilepsy and anti-epileptic medication usage and its association with bone diseases and fractures, as well as further investigation into optimal management of bone health in epilepsy. |
X Demographics
Geographical breakdown
Country | Count | As % |
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United Kingdom | 1 | 33% |
Netherlands | 1 | 33% |
Unknown | 1 | 33% |
Demographic breakdown
Type | Count | As % |
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Scientists | 2 | 67% |
Practitioners (doctors, other healthcare professionals) | 1 | 33% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Unknown | 49 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Researcher | 7 | 14% |
Student > Doctoral Student | 6 | 12% |
Student > Bachelor | 5 | 10% |
Student > Master | 5 | 10% |
Student > Ph. D. Student | 5 | 10% |
Other | 10 | 20% |
Unknown | 11 | 22% |
Readers by discipline | Count | As % |
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Medicine and Dentistry | 15 | 31% |
Pharmacology, Toxicology and Pharmaceutical Science | 8 | 16% |
Nursing and Health Professions | 4 | 8% |
Unspecified | 2 | 4% |
Biochemistry, Genetics and Molecular Biology | 1 | 2% |
Other | 4 | 8% |
Unknown | 15 | 31% |