| Title |
A SCARECROW-based regulatory circuit controls Arabidopsis thaliana meristem size from the root endodermis
|
|---|---|
| Published in |
Planta, February 2016
|
| DOI | 10.1007/s00425-016-2471-0 |
| Pubmed ID | |
| Authors |
Laila Moubayidin, Elena Salvi, Leonardo Giustini, Inez Terpstra, Renze Heidstra, Paolo Costantino, Sabrina Sabatini |
| Abstract |
SCARECROW controls Arabidopsis root meristem size from the root endodermis tissue by regulating the DELLA protein RGA that in turn mediates the regulation of ARR1 levels at the transition zone. Coherent organ growth requires a fine balance between cell division and cell differentiation. Intriguingly, plants continuously develop organs post-embryonically thanks to the activity of meristems that allow growth and environmental plasticity. In Arabidopsis thaliana, continued root growth is assured when division of the distal stem cell and their daughters is balanced with cell differentiation at the meristematic transition zone (TZ). We have previously shown that at the TZ, the cytokinin-dependent transcription factor ARR1 controls the rate of differentiation commitment of meristematic cells and that its activities are coordinated with those of the distal stem cells by the gene SCARECROW (SCR). In the stem cell organizer (the quiescent center, QC), SCR directly suppresses ARR1 both sustaining stem cell activities and titrating non-autonomously the ARR1 transcript levels at the TZ via auxin. Here, we show that SCR also exerts a fine control on ARR1 levels at the TZ from the endodermis by sustaining gibberellin signals. From the endodermis, SCR controls the RGA REPRESSOR OF ga1-3 (RGA) DELLA protein stability throughout the root meristem, thus controlling ARR1 transcriptional activation at the TZ. This guarantees robustness and fineness to the control of ARR1 levels necessary to balance cell division to cell differentiation in sustaining coherent root growth. Therefore, this work advances the state of the art in the field of root meristem development by integrating the activity of three hormones, auxin, gibberellin, and cytokinin, under the control of different tissue-specific activities of a single root key regulator, SCR. |
Mendeley readers
The data shown below were compiled from readership statistics for 85 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 1 | 1% |
| Germany | 1 | 1% |
| Unknown | 83 | 98% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 26 | 31% |
| Researcher | 12 | 14% |
| Student > Doctoral Student | 11 | 13% |
| Student > Master | 7 | 8% |
| Student > Bachelor | 3 | 4% |
| Other | 8 | 9% |
| Unknown | 18 | 21% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 43 | 51% |
| Biochemistry, Genetics and Molecular Biology | 21 | 25% |
| Unspecified | 1 | 1% |
| Design | 1 | 1% |
| Unknown | 19 | 22% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 23 February 2016.
All research outputs
#17,787,961
of 22,849,304 outputs
Outputs from Planta
#2,049
of 2,720 outputs
Outputs of similar age
#270,800
of 397,235 outputs
Outputs of similar age from Planta
#19
of 35 outputs
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