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Efficacy and safety of oral strontium ranelate for the treatment of knee osteoarthritis: rationale and design of randomised, double-blind, placebo-controlled trial

Overview of attention for article published in Current Medical Research & Opinion, January 2012
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  • Average Attention Score compared to outputs of the same age
  • Above-average Attention Score compared to outputs of the same age and source (53rd percentile)

Mentioned by

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3 X users

Citations

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40 Dimensions

Readers on

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57 Mendeley
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Title
Efficacy and safety of oral strontium ranelate for the treatment of knee osteoarthritis: rationale and design of randomised, double-blind, placebo-controlled trial
Published in
Current Medical Research & Opinion, January 2012
DOI 10.1185/03007995.2011.648758
Pubmed ID
Authors

Cyrus Cooper, Jean-Yves Reginster, Roland Chapurlat, Claus Christiansen, Harry Genant, Nicholas Bellamy, William Bensen, Federico Navarro, Janusz Badurski, Evgeny Nasonov, Xavier Chevalier, Philip N. Sambrook

Abstract

The osteoporosis drug strontium ranelate dissociates bone remodelling processes. It also inhibits subchondral bone resorption and stimulates cartilage matrix formation in vitro. Exploratory studies in the osteoporosis trials report that strontium ranelate reduces biomarkers of cartilage degradation, and attenuates the progression and clinical symptoms of spinal osteoarthritis, suggesting symptom- and structure-modifying activity in osteoarthritis. We describe the rationale and design of a randomised trial evaluating the efficacy and safety of strontium ranelate in knee osteoarthritis.

X Demographics

X Demographics

The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 57 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 2%
Denmark 1 2%
Unknown 55 96%

Demographic breakdown

Readers by professional status Count As %
Researcher 8 14%
Student > Master 7 12%
Student > Bachelor 6 11%
Student > Ph. D. Student 5 9%
Professor 4 7%
Other 12 21%
Unknown 15 26%
Readers by discipline Count As %
Medicine and Dentistry 24 42%
Biochemistry, Genetics and Molecular Biology 3 5%
Pharmacology, Toxicology and Pharmaceutical Science 2 4%
Business, Management and Accounting 2 4%
Nursing and Health Professions 2 4%
Other 8 14%
Unknown 16 28%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 30 April 2012.
All research outputs
#16,073,220
of 25,411,814 outputs
Outputs from Current Medical Research & Opinion
#2,052
of 3,665 outputs
Outputs of similar age
#162,308
of 251,239 outputs
Outputs of similar age from Current Medical Research & Opinion
#23
of 49 outputs
Altmetric has tracked 25,411,814 research outputs across all sources so far. This one is in the 34th percentile – i.e., 34% of other outputs scored the same or lower than it.
So far Altmetric has tracked 3,665 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.1. This one is in the 40th percentile – i.e., 40% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 251,239 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 33rd percentile – i.e., 33% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 49 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 53% of its contemporaries.