| Title |
The distribution pattern of critically short telomeres in human osteoarthritic knees
|
|---|---|
| Published in |
Arthritis Research & Therapy, January 2012
|
| DOI | 10.1186/ar3687 |
| Pubmed ID | |
| Authors |
Maria Harbo, Laila Bendix, Anne-Christine Bay-Jensen, Jesper Graakjaer, Kent Søe, Thomas L Andersen, Per Kjaersgaard-Andersen, Steen Koelvraa, Jean-Marie Delaisse |
| Abstract |
Telomere shortening is associated with a number of common age-related diseases. A role of telomere shortening in osteoarthritis (OA) has been suggested, mainly based on the assessment of mean telomere length in ex vivo expanded chondrocytes. We addressed this role directly in vivo by using a newly developed assay, which measures specifically the load of ultra-short single telomeres (below 1,500 base pairs), that is, the telomere subpopulation believed to promote cellular senescence. |
X Demographics
The data shown below were collected from the profiles of 5 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 2 | 40% |
| France | 1 | 20% |
| Netherlands | 1 | 20% |
| Unknown | 1 | 20% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Scientists | 2 | 40% |
| Members of the public | 2 | 40% |
| Science communicators (journalists, bloggers, editors) | 1 | 20% |
Mendeley readers
The data shown below were compiled from readership statistics for 62 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Denmark | 3 | 5% |
| South Africa | 1 | 2% |
| Unknown | 58 | 94% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 15 | 24% |
| Student > Master | 8 | 13% |
| Student > Ph. D. Student | 7 | 11% |
| Other | 5 | 8% |
| Lecturer | 4 | 6% |
| Other | 11 | 18% |
| Unknown | 12 | 19% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 14 | 23% |
| Biochemistry, Genetics and Molecular Biology | 13 | 21% |
| Agricultural and Biological Sciences | 12 | 19% |
| Immunology and Microbiology | 2 | 3% |
| Nursing and Health Professions | 2 | 3% |
| Other | 6 | 10% |
| Unknown | 13 | 21% |
Attention Score in Context
This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 12 February 2012.
All research outputs
#15,169,543
of 25,374,647 outputs
Outputs from Arthritis Research & Therapy
#2,203
of 3,381 outputs
Outputs of similar age
#155,870
of 251,545 outputs
Outputs of similar age from Arthritis Research & Therapy
#33
of 56 outputs
Altmetric has tracked 25,374,647 research outputs across all sources so far. This one is in the 38th percentile – i.e., 38% of other outputs scored the same or lower than it.
So far Altmetric has tracked 3,381 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 9.2. This one is in the 33rd percentile – i.e., 33% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 251,545 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 36th percentile – i.e., 36% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 56 others from the same source and published within six weeks on either side of this one. This one is in the 39th percentile – i.e., 39% of its contemporaries scored the same or lower than it.