Title |
Management of Hepatitis C Antiviral Therapy Adverse Effects
|
---|---|
Published in |
Current Hepatology Reports, December 2010
|
DOI | 10.1007/s11901-010-0078-7 |
Pubmed ID | |
Authors |
Hubert Sung, Michael Chang, Sammy Saab |
Abstract |
Hepatitis C is one of the leading causes of liver disease in the United States, affecting more than 4 million individuals. The current treatment regimen involves pegylated interferon in combination with ribavirin. Although antiviral treatment has been associated with a greater than 50% sustained viral response rate, the adverse effects have proven to be detrimental to quality of life and therapy adherence, and consequently lead to lower sustained viral response rates. This article identifies the most frequently described complications associated with pegylated interferon and ribavirin. The active management of these complications is discussed, including both preventive and empiric treatments. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 61 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 13 | 21% |
Student > Master | 12 | 20% |
Student > Bachelor | 5 | 8% |
Other | 4 | 7% |
Researcher | 4 | 7% |
Other | 11 | 18% |
Unknown | 12 | 20% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 24 | 39% |
Biochemistry, Genetics and Molecular Biology | 5 | 8% |
Pharmacology, Toxicology and Pharmaceutical Science | 4 | 7% |
Immunology and Microbiology | 4 | 7% |
Agricultural and Biological Sciences | 3 | 5% |
Other | 9 | 15% |
Unknown | 12 | 20% |