| Title |
Expression of stem cell and epithelial-mesenchymal transition markers in primary breast cancer patients with circulating tumor cells
|
|---|---|
| Published in |
Breast Cancer Research, January 2012
|
| DOI | 10.1186/bcr3099 |
| Pubmed ID | |
| Authors |
Sabine Kasimir-Bauer, Oliver Hoffmann, Diethelm Wallwiener, Rainer Kimmig, Tanja Fehm |
| Abstract |
The presence of circulating tumor cells (CTC) in breast cancer might be associated with stem cell-like tumor cells which have been suggested to be the active source of metastatic spread in primary tumors. Furthermore, to be able to disseminate and metastasize, CTC must be able to perform epithelial-mesenchymal transition (EMT). We studied the expression of three EMT markers and the stem cell marker ALDH1 in CTC from 502 primary breast cancer patients. Data were correlated with the presence of disseminated tumor cells (DTC) in the bone marrow (BM) and with clinicopathological data of the patients. |
X Demographics
The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 3 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 2 | 67% |
| Practitioners (doctors, other healthcare professionals) | 1 | 33% |
Mendeley readers
The data shown below were compiled from readership statistics for 214 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 5 | 2% |
| Portugal | 2 | <1% |
| Spain | 2 | <1% |
| India | 1 | <1% |
| Germany | 1 | <1% |
| Italy | 1 | <1% |
| China | 1 | <1% |
| Unknown | 201 | 94% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 49 | 23% |
| Student > Ph. D. Student | 47 | 22% |
| Student > Master | 22 | 10% |
| Student > Bachelor | 16 | 7% |
| Student > Doctoral Student | 14 | 7% |
| Other | 35 | 16% |
| Unknown | 31 | 14% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 54 | 25% |
| Medicine and Dentistry | 51 | 24% |
| Biochemistry, Genetics and Molecular Biology | 42 | 20% |
| Engineering | 19 | 9% |
| Chemistry | 3 | 1% |
| Other | 7 | 3% |
| Unknown | 38 | 18% |
Attention Score in Context
This research output has an Altmetric Attention Score of 5. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 15 April 2022.
All research outputs
#7,204,882
of 25,373,627 outputs
Outputs from Breast Cancer Research
#824
of 2,052 outputs
Outputs of similar age
#59,942
of 251,776 outputs
Outputs of similar age from Breast Cancer Research
#12
of 40 outputs
Altmetric has tracked 25,373,627 research outputs across all sources so far. This one has received more attention than most of these and is in the 71st percentile.
So far Altmetric has tracked 2,052 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 12.2. This one has gotten more attention than average, scoring higher than 59% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 251,776 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 75% of its contemporaries.
We're also able to compare this research output to 40 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 67% of its contemporaries.