| Title |
The balance of expression of PTPN22 splice forms is significantly different in rheumatoid arthritis patients compared with controls
|
|---|---|
| Published in |
Genome Medicine, January 2012
|
| DOI | 10.1186/gm301 |
| Pubmed ID | |
| Authors |
Marcus Ronninger, Yongjing Guo, Klementy Shchetynsky, Andrew Hill, Mohsen Khademi, Tomas Olsson, Padmalatha S Reddy, Maria Seddighzadeh, James D Clark, Lih-Ling Lin, Margot O'Toole, Leonid Padyukov |
| Abstract |
The R620W variant in protein tyrosine phosphatase non-receptor 22 (PTPN22) is associated with rheumatoid arthritis (RA). The PTPN22 gene has alternatively spliced transcripts and at least two of the splice forms have been confirmed to encode different PTPN22 (LYP) proteins, but detailed information regarding expression of these is lacking, especially with regard to autoimmune diseases. |
X Demographics
The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 2 | 67% |
| Unknown | 1 | 33% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 2 | 67% |
| Scientists | 1 | 33% |
Mendeley readers
The data shown below were compiled from readership statistics for 31 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Brazil | 1 | 3% |
| Sweden | 1 | 3% |
| United Kingdom | 1 | 3% |
| Thailand | 1 | 3% |
| United States | 1 | 3% |
| Unknown | 26 | 84% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 7 | 23% |
| Student > Master | 6 | 19% |
| Student > Ph. D. Student | 5 | 16% |
| Student > Bachelor | 2 | 6% |
| Other | 2 | 6% |
| Other | 3 | 10% |
| Unknown | 6 | 19% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 9 | 29% |
| Medicine and Dentistry | 6 | 19% |
| Biochemistry, Genetics and Molecular Biology | 4 | 13% |
| Immunology and Microbiology | 4 | 13% |
| Nursing and Health Professions | 1 | 3% |
| Other | 0 | 0% |
| Unknown | 7 | 23% |
Attention Score in Context
This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 23 January 2012.
All research outputs
#16,722,190
of 25,374,917 outputs
Outputs from Genome Medicine
#1,429
of 1,585 outputs
Outputs of similar age
#168,316
of 251,774 outputs
Outputs of similar age from Genome Medicine
#19
of 21 outputs
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