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Innovative Collagen Nano‐Hydroxyapatite Scaffolds Offer a Highly Efficient Non‐Viral Gene Delivery Platform for Stem Cell‐Mediated Bone Formation

Overview of attention for article published in Advanced Materials, January 2012
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Title
Innovative Collagen Nano‐Hydroxyapatite Scaffolds Offer a Highly Efficient Non‐Viral Gene Delivery Platform for Stem Cell‐Mediated Bone Formation
Published in
Advanced Materials, January 2012
DOI 10.1002/adma.201103828
Pubmed ID
Authors

Caroline M. Curtin, Gráinne M. Cunniffe, Frank G. Lyons, Kazuhisa Bessho, Glenn R. Dickson, Garry P. Duffy, Fergal J. O'Brien

Abstract

The ability of nano-hydroxyapatite (nHA) particles developed in-house to act as non-viral delivery vectors is assessed. These nHA particles are combined with collagen to yield bioactive, biodegradable collagen nano-hydroxyapatite (coll-nHA) scaffolds. Their ability to act as gene-activated matrices for BMP2 delivery is demonstrated with successful transfection of mesenchymal stem cells (MSCs) resulting in high calcium production.

X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 167 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Ireland 2 1%
Colombia 1 <1%
United Kingdom 1 <1%
China 1 <1%
Spain 1 <1%
Unknown 161 96%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 52 31%
Researcher 25 15%
Student > Master 16 10%
Student > Doctoral Student 10 6%
Student > Postgraduate 9 5%
Other 31 19%
Unknown 24 14%
Readers by discipline Count As %
Engineering 31 19%
Agricultural and Biological Sciences 24 14%
Materials Science 23 14%
Biochemistry, Genetics and Molecular Biology 19 11%
Medicine and Dentistry 16 10%
Other 27 16%
Unknown 27 16%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 05 August 2012.
All research outputs
#16,727,629
of 24,602,766 outputs
Outputs from Advanced Materials
#12,356
of 16,555 outputs
Outputs of similar age
#173,043
of 253,274 outputs
Outputs of similar age from Advanced Materials
#118
of 141 outputs
Altmetric has tracked 24,602,766 research outputs across all sources so far. This one is in the 21st percentile – i.e., 21% of other outputs scored the same or lower than it.
So far Altmetric has tracked 16,555 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 11.1. This one is in the 20th percentile – i.e., 20% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 253,274 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 20th percentile – i.e., 20% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 141 others from the same source and published within six weeks on either side of this one. This one is in the 10th percentile – i.e., 10% of its contemporaries scored the same or lower than it.