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Estimating the Duration of Pertussis Immunity Using Epidemiological Signatures

Overview of attention for article published in PLoS Pathogens, October 2009
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (89th percentile)
  • High Attention Score compared to outputs of the same age and source (84th percentile)

Mentioned by

blogs
1 blog
twitter
6 X users
facebook
2 Facebook pages

Citations

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130 Dimensions

Readers on

mendeley
143 Mendeley
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1 CiteULike
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Title
Estimating the Duration of Pertussis Immunity Using Epidemiological Signatures
Published in
PLoS Pathogens, October 2009
DOI 10.1371/journal.ppat.1000647
Pubmed ID
Authors

Helen J. Wearing, Pejman Rohani

Abstract

Case notifications of pertussis have shown an increase in a number of countries with high rates of routine pediatric immunization. This has led to significant public health concerns over a possible pertussis re-emergence. A leading proposed explanation for the observed increase in incidence is the loss of immunity to pertussis, which is known to occur after both natural infection and vaccination. Little is known, however, about the typical duration of immunity and its epidemiological implications. Here, we analyze a simple mathematical model, exploring specifically the inter-epidemic period and fade-out frequency. These predictions are then contrasted with detailed incidence data for England and Wales. We find model output to be most sensitive to assumptions concerning naturally acquired immunity, which allows us to estimate the average duration of immunity. Our results support a period of natural immunity that is, on average, long-lasting (at least 30 years) but inherently variable.

X Demographics

X Demographics

The data shown below were collected from the profiles of 6 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 143 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 5 3%
Australia 4 3%
France 3 2%
United States 2 1%
Kenya 1 <1%
Austria 1 <1%
Chile 1 <1%
Brazil 1 <1%
Korea, Republic of 1 <1%
Other 2 1%
Unknown 122 85%

Demographic breakdown

Readers by professional status Count As %
Researcher 35 24%
Student > Ph. D. Student 30 21%
Student > Master 14 10%
Professor > Associate Professor 11 8%
Student > Bachelor 9 6%
Other 34 24%
Unknown 10 7%
Readers by discipline Count As %
Agricultural and Biological Sciences 33 23%
Medicine and Dentistry 26 18%
Mathematics 22 15%
Immunology and Microbiology 14 10%
Biochemistry, Genetics and Molecular Biology 4 3%
Other 20 14%
Unknown 24 17%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 12. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 21 May 2018.
All research outputs
#3,112,361
of 25,374,917 outputs
Outputs from PLoS Pathogens
#2,895
of 9,467 outputs
Outputs of similar age
#11,213
of 108,322 outputs
Outputs of similar age from PLoS Pathogens
#12
of 75 outputs
Altmetric has tracked 25,374,917 research outputs across all sources so far. Compared to these this one has done well and is in the 87th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 9,467 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 20.4. This one has gotten more attention than average, scoring higher than 69% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 108,322 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 89% of its contemporaries.
We're also able to compare this research output to 75 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 84% of its contemporaries.