| Title |
Brain structure and function in borderline personality disorder
|
|---|---|
| Published in |
Brain Structure and Function, January 2012
|
| DOI | 10.1007/s00429-012-0379-4 |
| Pubmed ID | |
| Authors |
Aisling O’Neill, Thomas Frodl |
| Abstract |
The spotlight on borderline personality disorder (BPD) has been growing in recent years, with the number of papers discussing potential causes and triggers of the disorder rapidly on the increase. Also on the increase, though still lacking sufficient numbers to produce well-supported hypotheses, are studies employing neuroimaging techniques as investigative tools in BPD. In this review, we investigate the current state and findings of neuroimaging studies in BPD, focusing in particular, on the studies examining structural, functional, and neurometabolic abnormalities in the disorder. Some suspected trends in the data are highlighted, including reductions in the hippocampi and amygdalae of BPD patients compared to healthy controls, exaggerated amygdala activity in BPD patients when confronted with emotion-related stimulus, and negative correlations between increases in left amygdalar creatine and reductions in amygdalar volume, reductions in absolute N-acetylaspartate concentration in the dorsolateral prefrontal cortex of BPD patients, and increases in glutamate concentration in the anterior cingulate cortices of BPD patients. We also discuss the limitations of some of the current studies including hindrances due to sample effects and techniques used and the potential of future neuroimaging research in BPD. |
Mendeley readers
The data shown below were compiled from readership statistics for 151 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 3 | 2% |
| Switzerland | 1 | <1% |
| Austria | 1 | <1% |
| Netherlands | 1 | <1% |
| Spain | 1 | <1% |
| Sweden | 1 | <1% |
| Unknown | 143 | 95% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 23 | 15% |
| Student > Bachelor | 22 | 15% |
| Researcher | 19 | 13% |
| Student > Master | 19 | 13% |
| Student > Doctoral Student | 12 | 8% |
| Other | 26 | 17% |
| Unknown | 30 | 20% |
| Readers by discipline | Count | As % |
|---|---|---|
| Psychology | 63 | 42% |
| Medicine and Dentistry | 20 | 13% |
| Agricultural and Biological Sciences | 13 | 9% |
| Neuroscience | 11 | 7% |
| Social Sciences | 2 | 1% |
| Other | 11 | 7% |
| Unknown | 31 | 21% |
Attention Score in Context
This research output has an Altmetric Attention Score of 13. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 08 August 2023.
All research outputs
#2,490,089
of 24,217,893 outputs
Outputs from Brain Structure and Function
#160
of 1,725 outputs
Outputs of similar age
#19,456
of 253,046 outputs
Outputs of similar age from Brain Structure and Function
#2
of 12 outputs
Altmetric has tracked 24,217,893 research outputs across all sources so far. Compared to these this one has done well and is in the 89th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,725 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 7.0. This one has done particularly well, scoring higher than 90% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 253,046 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 92% of its contemporaries.
We're also able to compare this research output to 12 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 83% of its contemporaries.