Title |
Association Between BRCA1 and BRCA2 Mutations and Survival in Women With Invasive Epithelial Ovarian Cancer
|
---|---|
Published in |
JAMA: Journal of the American Medical Association, January 2012
|
DOI | 10.1001/jama.2012.20 |
Pubmed ID | |
Authors |
Kelly L. Bolton, Georgia Chenevix- Trench, Cindy Goh, Siegal Sadetzki, Susan J. Ramus, Beth Y. Karlan, Diether Lambrechts, Evelyn Despierre, Daniel Barrowdale, Lesley McGuffog, Sue Healey, Douglas F. Easton, Olga Sinilnikova, Javier Benítez, María J. García, Susan Neuhausen, Mitchell H. Gail, Patricia Hartge, Susan Peock, Debra Frost, D. Gareth Evans, Rosalind Eeles, Andrew K. Godwin, Mary B. Daly, Ava Kwong, Edmond S. K., Conxi Lázaro, Ignacio Blanco, Marco Montagna, Emma D'Andrea, Maria Ornella Nicoletto, Sharon E. Johnatty, Susanne Krüger Kjær, Allan Jensen, Estrid Høgdall, Ellen L. Goode, Brooke L. Fridley, Jennifer T. Loud, Mark H. Greene, Phuong L. Mai, Angela Chetrit, Flora Lubin, Galit Hirsh-Yechezkel, Gord Glendon, Irene L. Andrulis, Amanda E. Toland, Leigha Senter, Martin E. Gore, Charlie Gourley, Caroline O. Michie, Honglin Song, Jonathan Tyrer, Alice S. Whittemore, Valerie McGuire, Weiva Sieh, Ulf Kristoffersson, Håkan Olsson, Åke Borg, Douglas A. Levine, Linda Steele, Mary S. Beattie, Salina Chan, Robert L. Nussbaum, Kirsten B. Moysich, Jenny Gross, Ilana Cass, Christine Walsh, Andrew J. Li, Ronald Leuchter, Ora Gordon, Montserrat Garcia-Closas, Simon A. Gayther, Stephen J. Chanock, Antonis C. Antoniou, Paul D. P. Pharoah, and The Cancer Genome Atlas Research Network for the EMBRACE kConFab Investigators |
Abstract |
Approximately 10% of women with invasive epithelial ovarian cancer (EOC) carry deleterious germline mutations in BRCA1 or BRCA2. A recent article suggested that BRCA2-related EOC was associated with an improved prognosis, but the effect of BRCA1 remains unclear. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 5 | 36% |
Spain | 2 | 14% |
Belgium | 1 | 7% |
Turkey | 1 | 7% |
Unknown | 5 | 36% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 7 | 50% |
Scientists | 5 | 36% |
Practitioners (doctors, other healthcare professionals) | 2 | 14% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 4 | 1% |
United Kingdom | 1 | <1% |
Netherlands | 1 | <1% |
Greece | 1 | <1% |
Unknown | 299 | 98% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 51 | 17% |
Researcher | 47 | 15% |
Student > Bachelor | 30 | 10% |
Other | 29 | 9% |
Student > Master | 27 | 9% |
Other | 55 | 18% |
Unknown | 67 | 22% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 113 | 37% |
Agricultural and Biological Sciences | 46 | 15% |
Biochemistry, Genetics and Molecular Biology | 37 | 12% |
Engineering | 7 | 2% |
Pharmacology, Toxicology and Pharmaceutical Science | 5 | 2% |
Other | 22 | 7% |
Unknown | 76 | 25% |