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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Role of T-cell activation in salt-sensitive hypertension
|
|---|---|
| Published in |
American Journal of Physiology: Heart & Circulatory Physiology, March 2019
|
| DOI | 10.1152/ajpheart.00096.2019 |
| Pubmed ID | |
| Authors |
Jiafa Ren, Steven D Crowley |
| Abstract |
The contributions of T lymphocytes to the pathogenesis of salt-sensitive hypertension has been well established. Under hypertensive stimuli, naïve T cells develop into different subsets, including Th1, Th2, Th17, Treg and cytotoxic CD8+ T cells, depending on the surrounding microenviroment in organs. Distinct subsets of T cells may play totally different roles in tissue damage and hypertension. The underlying mechanisms by which hypertensive stimuli activate naïve T cells involve many events and different organs, such as neoantigen presentation by dendritic cells, high salt concentration, the milieu of oxidative stress in the kidney and vasculature. Infiltrating and activated T subsets in injured organs, in turn, exert considerable impacts on tissue dysfunction, including sodium retention in the kidney, vascular stiffness and remodeling in vasculature. Therefore, a thorough knowledge of T cell actions in hypertension may provide novel insights for the development of new therapeutic strategies for patients with hypertension. |
X Demographics
The data shown below were collected from the profiles of 14 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 7 | 50% |
| Argentina | 1 | 7% |
| United Kingdom | 1 | 7% |
| Unknown | 5 | 36% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Scientists | 7 | 50% |
| Members of the public | 5 | 36% |
| Science communicators (journalists, bloggers, editors) | 2 | 14% |
Mendeley readers
The data shown below were compiled from readership statistics for 51 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 51 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 10 | 20% |
| Student > Bachelor | 4 | 8% |
| Professor > Associate Professor | 4 | 8% |
| Student > Master | 4 | 8% |
| Researcher | 3 | 6% |
| Other | 9 | 18% |
| Unknown | 17 | 33% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 13 | 25% |
| Agricultural and Biological Sciences | 3 | 6% |
| Immunology and Microbiology | 3 | 6% |
| Nursing and Health Professions | 2 | 4% |
| Pharmacology, Toxicology and Pharmaceutical Science | 2 | 4% |
| Other | 4 | 8% |
| Unknown | 24 | 47% |
Attention Score in Context
This research output has an Altmetric Attention Score of 9. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 04 October 2021.
All research outputs
#4,303,041
of 25,385,509 outputs
Outputs from American Journal of Physiology: Heart & Circulatory Physiology
#616
of 4,028 outputs
Outputs of similar age
#85,752
of 363,396 outputs
Outputs of similar age from American Journal of Physiology: Heart & Circulatory Physiology
#14
of 73 outputs
Altmetric has tracked 25,385,509 research outputs across all sources so far. Compared to these this one has done well and is in the 83rd percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 4,028 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.7. This one has done well, scoring higher than 84% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 363,396 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 76% of its contemporaries.
We're also able to compare this research output to 73 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 80% of its contemporaries.