Title |
Keloids and Hypertrophic Scars: A Spectrum of Clinical Challenges
|
---|---|
Published in |
American Journal of Clinical Dermatology, February 2016
|
DOI | 10.1007/s40257-016-0175-7 |
Pubmed ID | |
Authors |
Anthony P. Trace, Clinton W. Enos, Alon Mantel, Valerie M. Harvey |
Abstract |
Since their earliest description, keloids and hypertrophic scars have beleaguered patients and clinicians alike. These scars can be aesthetically disfiguring, functionally debilitating, emotionally distressing, and psychologically damaging, culminating in a significant burden for patients. Our current understanding of keloid pathophysiology has grown and continues to advance while molecular biology, genetics, and technology provide ever-deepening insight into the nature of wound healing and the pathologic perturbations thereof. Greater understanding will lead to the development and application of refined therapeutic modalities. This article provides an overview of our current understanding of keloids, highlighting clinical characteristics and diagnostic criteria while providing a comprehensive summary of the many therapeutic modalities available. The proposed mechanism, application, adverse events, and reported efficacy of each modality is evaluated, and current recommendations are summarized. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Switzerland | 1 | 100% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United Kingdom | 1 | <1% |
Unknown | 146 | 99% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Bachelor | 24 | 16% |
Researcher | 15 | 10% |
Student > Postgraduate | 13 | 9% |
Student > Master | 12 | 8% |
Student > Ph. D. Student | 11 | 7% |
Other | 23 | 16% |
Unknown | 49 | 33% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 60 | 41% |
Biochemistry, Genetics and Molecular Biology | 15 | 10% |
Nursing and Health Professions | 4 | 3% |
Agricultural and Biological Sciences | 4 | 3% |
Computer Science | 2 | 1% |
Other | 9 | 6% |
Unknown | 53 | 36% |