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Early measurements of plasma matrix metalloproteinase-2 predict infarct size and ventricular dysfunction in ST-elevation myocardial infarction

Overview of attention for article published in Heart, July 2011
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Title
Early measurements of plasma matrix metalloproteinase-2 predict infarct size and ventricular dysfunction in ST-elevation myocardial infarction
Published in
Heart, July 2011
DOI 10.1136/heartjnl-2011-300079
Pubmed ID
Authors

Lennart Nilsson, Jonas Hallén, Dan Atar, Lena Jonasson, Eva Swahn

Abstract

Immediate reopening of the acutely occluded infarct-related artery via primary PCI is the preferred treatment in ST-elevation myocardial infarction (STEMI). However, the sudden reinitiation of blood flow can lead to a local acute inflammatory response with further endothelial and myocardial damage, so-called reperfusion injury. The activation of matrix metalloproteinases (MMPs) is suggested to be a key event in this process.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 41 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 41 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 12 29%
Student > Doctoral Student 5 12%
Other 5 12%
Student > Ph. D. Student 4 10%
Lecturer 2 5%
Other 6 15%
Unknown 7 17%
Readers by discipline Count As %
Medicine and Dentistry 17 41%
Agricultural and Biological Sciences 3 7%
Pharmacology, Toxicology and Pharmaceutical Science 3 7%
Nursing and Health Professions 2 5%
Biochemistry, Genetics and Molecular Biology 2 5%
Other 4 10%
Unknown 10 24%