Title |
Contractile activity of human skeletal muscle cells prevents insulin resistance by inhibiting pro-inflammatory signalling pathways
|
---|---|
Published in |
Diabetologia, January 2012
|
DOI | 10.1007/s00125-012-2454-z |
Pubmed ID | |
Authors |
S. Lambernd, A. Taube, A. Schober, B. Platzbecker, S. W. Görgens, R. Schlich, K. Jeruschke, J. Weiss, K. Eckardt, J. Eckel |
Abstract |
Obesity is closely associated with muscle insulin resistance and is a major risk factor for the pathogenesis of type 2 diabetes. Regular physical activity not only prevents obesity, but also considerably improves insulin sensitivity and skeletal muscle metabolism. We sought to establish and characterise an in vitro model of human skeletal muscle contraction, with a view to directly studying the signalling pathways and mechanisms that are involved in the beneficial effects of muscle activity. |
X Demographics
The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
Country | Count | As % |
---|---|---|
United Kingdom | 2 | 67% |
United States | 1 | 33% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 2 | 67% |
Scientists | 1 | 33% |
Mendeley readers
The data shown below were compiled from readership statistics for 189 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
Country | Count | As % |
---|---|---|
United Kingdom | 3 | 2% |
Brazil | 1 | <1% |
Sweden | 1 | <1% |
Denmark | 1 | <1% |
Japan | 1 | <1% |
United States | 1 | <1% |
Unknown | 181 | 96% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 46 | 24% |
Student > Master | 33 | 17% |
Researcher | 22 | 12% |
Student > Bachelor | 14 | 7% |
Student > Doctoral Student | 12 | 6% |
Other | 29 | 15% |
Unknown | 33 | 17% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 42 | 22% |
Biochemistry, Genetics and Molecular Biology | 40 | 21% |
Medicine and Dentistry | 27 | 14% |
Sports and Recreations | 20 | 11% |
Neuroscience | 3 | 2% |
Other | 15 | 8% |
Unknown | 42 | 22% |
Attention Score in Context
This research output has an Altmetric Attention Score of 6. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 27 February 2024.
All research outputs
#4,666,782
of 22,662,201 outputs
Outputs from Diabetologia
#1,990
of 5,023 outputs
Outputs of similar age
#41,650
of 246,348 outputs
Outputs of similar age from Diabetologia
#13
of 55 outputs
Altmetric has tracked 22,662,201 research outputs across all sources so far. Compared to these this one has done well and is in the 76th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 5,023 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 22.6. This one has gotten more attention than average, scoring higher than 54% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 246,348 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 80% of its contemporaries.
We're also able to compare this research output to 55 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 69% of its contemporaries.