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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Somatic histone H3 alterations in pediatric diffuse intrinsic pontine gliomas and non-brainstem glioblastomas
|
|---|---|
| Published in |
Nature Genetics, January 2012
|
| DOI | 10.1038/ng.1102 |
| Pubmed ID | |
| Abstract |
To identify somatic mutations in pediatric diffuse intrinsic pontine glioma (DIPG), we performed whole-genome sequencing of DNA from seven DIPGs and matched germline tissue and targeted sequencing of an additional 43 DIPGs and 36 non-brainstem pediatric glioblastomas (non-BS-PGs). We found that 78% of DIPGs and 22% of non-BS-PGs contained a mutation in H3F3A, encoding histone H3.3, or in the related HIST1H3B, encoding histone H3.1, that caused a p.Lys27Met amino acid substitution in each protein. An additional 14% of non-BS-PGs had somatic mutations in H3F3A causing a p.Gly34Arg alteration. |
X Demographics
The data shown below were collected from the profiles of 12 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 4 | 33% |
| United States | 3 | 25% |
| Australia | 1 | 8% |
| Unknown | 4 | 33% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 7 | 58% |
| Scientists | 4 | 33% |
| Science communicators (journalists, bloggers, editors) | 1 | 8% |
Mendeley readers
The data shown below were compiled from readership statistics for 877 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 4 | <1% |
| Netherlands | 2 | <1% |
| United Kingdom | 2 | <1% |
| Spain | 2 | <1% |
| France | 2 | <1% |
| Canada | 2 | <1% |
| Austria | 1 | <1% |
| Sweden | 1 | <1% |
| Czechia | 1 | <1% |
| Other | 9 | 1% |
| Unknown | 851 | 97% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 171 | 19% |
| Researcher | 154 | 18% |
| Student > Bachelor | 98 | 11% |
| Student > Master | 88 | 10% |
| Student > Postgraduate | 50 | 6% |
| Other | 154 | 18% |
| Unknown | 162 | 18% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 211 | 24% |
| Agricultural and Biological Sciences | 206 | 23% |
| Medicine and Dentistry | 160 | 18% |
| Neuroscience | 35 | 4% |
| Chemistry | 15 | 2% |
| Other | 66 | 8% |
| Unknown | 184 | 21% |
Attention Score in Context
This research output has an Altmetric Attention Score of 51. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 20 March 2024.
All research outputs
#844,370
of 25,837,817 outputs
Outputs from Nature Genetics
#1,531
of 7,639 outputs
Outputs of similar age
#4,899
of 256,285 outputs
Outputs of similar age from Nature Genetics
#6
of 86 outputs
Altmetric has tracked 25,837,817 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 96th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 7,639 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 43.7. This one has done well, scoring higher than 79% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 256,285 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 98% of its contemporaries.
We're also able to compare this research output to 86 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 93% of its contemporaries.