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Mendeley readers
| Title |
Glow discharge plasma deposition of tetraethylene glycol dimethyl ether for fouling‐resistant biomaterial surfaces
|
|---|---|
| Published in |
Journal of Biomedical Materials Research, September 2004
|
| DOI | 10.1002/jbm.820260402 |
| Pubmed ID | |
| Authors |
Gabriel P. Löpez, Buddy D. Ratner, Caren D. Tidwell, Claire L. Haycox, Richard J. Rapoza, Thomas A. Horbett |
| Abstract |
The glow discharge plasma deposition (GDPD) of tetraethylene glycol dimethyl ether is introduced as a novel method for obtaining surfaces that are resistant to protein adsorption and cellular attachment. Analysis of films by x-ray photoelectron spectroscopy and several biological assays indicate the formation of a fouling-resistant, PEO-like surface on several substrata (e.g., glass, polytetrafluoroethylene, polyethylene). Adsorption of 125I-radiolabelled proteins (fibrinogen, albumin and IgG) from buffer and plasma was very low (typically less than 20 ng/cm2) when compared to the untreated substrata, which exhibited much higher levels of protein adsorption. Not all coated substrata adsorbed equal amounts of protein (e.g., coated glass samples typically adsorbed more protein than coated polyethylene or coated polytetrafluoroethylene samples), suggesting that the substratum used may affect the amount of protein adsorbed. Measurement of dynamic platelet adhesion, using epifluorescent video microscopy, and endothelial cell attachment further demonstrates the short-term nonadhesiveness of these surfaces. |
Mendeley readers
The data shown below were compiled from readership statistics for 47 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 1 | 2% |
| Czechia | 1 | 2% |
| Switzerland | 1 | 2% |
| Unknown | 44 | 94% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 18 | 38% |
| Researcher | 6 | 13% |
| Student > Bachelor | 5 | 11% |
| Other | 3 | 6% |
| Student > Master | 3 | 6% |
| Other | 5 | 11% |
| Unknown | 7 | 15% |
| Readers by discipline | Count | As % |
|---|---|---|
| Engineering | 16 | 34% |
| Chemistry | 9 | 19% |
| Materials Science | 5 | 11% |
| Chemical Engineering | 4 | 9% |
| Agricultural and Biological Sciences | 3 | 6% |
| Other | 3 | 6% |
| Unknown | 7 | 15% |