| Title |
Therapeutic Liposomal Dry Powder Inhalation Aerosols for Targeted Lung Delivery
|
|---|---|
| Published in |
Lung, January 2012
|
| DOI | 10.1007/s00408-011-9360-x |
| Pubmed ID | |
| Authors |
Lauren Willis, Don Hayes, Heidi M. Mansour |
| Abstract |
Therapeutic liposomal powders (i.e., lipospheres and proliposomes) for dry powder inhalation aerosol delivery, formulated with phospholipids similar to endogenous lung surfactant, offer unique opportunities in pulmonary nanomedicine while offering controlled release and enhanced stability. Many pulmonary diseases such as lung cancer, tuberculosis (TB), cystic fibrosis (CF), bacterial and fungal lung infections, asthma, and chronic obstructive pulmonary disease (COPD) could greatly benefit from this type of pulmonary nanomedicine approach that can be delivered in a targeted manner by dry powder inhalers (DPIs). These delivery systems may require smaller doses for efficacy, exhibit reduced toxicity, fewer side effects, controlled drug release over a prolonged time period, and increased formulation stability as inhaled powders. This state-of-the-art review presents these novel aspects in depth. |
Mendeley readers
The data shown below were compiled from readership statistics for 199 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Iran, Islamic Republic of | 1 | <1% |
| Malaysia | 1 | <1% |
| United States | 1 | <1% |
| Saudi Arabia | 1 | <1% |
| Unknown | 195 | 98% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 39 | 20% |
| Student > Master | 34 | 17% |
| Researcher | 21 | 11% |
| Student > Bachelor | 14 | 7% |
| Professor > Associate Professor | 10 | 5% |
| Other | 37 | 19% |
| Unknown | 44 | 22% |
| Readers by discipline | Count | As % |
|---|---|---|
| Pharmacology, Toxicology and Pharmaceutical Science | 43 | 22% |
| Medicine and Dentistry | 31 | 16% |
| Agricultural and Biological Sciences | 21 | 11% |
| Engineering | 13 | 7% |
| Chemistry | 12 | 6% |
| Other | 29 | 15% |
| Unknown | 50 | 25% |
Attention Score in Context
This research output has an Altmetric Attention Score of 7. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 28 November 2023.
All research outputs
#4,144,712
of 22,662,201 outputs
Outputs from Lung
#104
of 883 outputs
Outputs of similar age
#36,267
of 246,172 outputs
Outputs of similar age from Lung
#2
of 15 outputs
Altmetric has tracked 22,662,201 research outputs across all sources so far. Compared to these this one has done well and is in the 80th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 883 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.2. This one has done well, scoring higher than 87% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 246,172 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 84% of its contemporaries.
We're also able to compare this research output to 15 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 86% of its contemporaries.