Title |
GAD65 Antigen Therapy in Recently Diagnosed Type 1 Diabetes Mellitus
|
---|---|
Published in |
New England Journal of Medicine, February 2012
|
DOI | 10.1056/nejmoa1107096 |
Pubmed ID | |
Authors |
Johnny Ludvigsson, David Krisky, Rosaura Casas, Tadej Battelino, Luis Castaño, James Greening, Olga Kordonouri, Timo Otonkoski, Paolo Pozzilli, Jean-Jacques Robert, Henk J Veeze, Jerry Palmer, Ulf Samuelsson, Helena Elding Larsson, Jan Åman, Gunilla Kärdell, Jan Neiderud Helsingborg, Göran Lundström, Eva Albinsson, Annelie Carlsson, Maria Nordvall, Hans Fors, Carl-Göran Arvidsson, Stig Edvardson, Ragnar Hanås, Karin Larsson, Björn Rathsman, Henrik Forsgren, Helena Desaix, Gun Forsander, Nils-Östen Nilsson, Carl-Göran Åkesson, Päivi Keskinen, Riitta Veijola, Timo Talvitie, Klemens Raile, Thomas Kapellen, Walter Burger, Andreas Neu, Ilse Engelsberger, Bettina Heidtmann, Suzanne Bechtold, David Leslie, Francesco Chiarelli, Alesandro Cicognani, Giuseppe Chiumello, Franco Cerutti, Gian Vincenzo Zuccotti, Ana Gomez Gila, Itxaso Rica, Raquel Barrio, Maria Clemente, Maria José López Garcia, Mercedes Rodriguez, Isabel Gonzalez, Juan Pedro Lopez, Mirentxu Oyarzabal, H M Reeser, Roos Nuboer, Pauline Stouthart, Natasa Bratina, Nina Bratanic, Marc de Kerdanet, Jacques Weill, Nicole Ser, Pascal Barat, Anne Marie Bertrand, Jean-Claude Carel, Rachel Reynaud, Regis Coutant, Sabine Baron |
Abstract |
The 65-kD isoform of glutamic acid decarboxylase (GAD65) is a major autoantigen in type 1 diabetes. We hypothesized that alum-formulated GAD65 (GAD-alum) can preserve beta-cell function in patients with recent-onset type 1 diabetes. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 5 | 36% |
Mexico | 1 | 7% |
Palestine, State of | 1 | 7% |
Chile | 1 | 7% |
Japan | 1 | 7% |
Brazil | 1 | 7% |
Unknown | 4 | 29% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 7 | 50% |
Practitioners (doctors, other healthcare professionals) | 5 | 36% |
Scientists | 1 | 7% |
Science communicators (journalists, bloggers, editors) | 1 | 7% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 3 | 2% |
Italy | 2 | 1% |
Netherlands | 1 | <1% |
New Zealand | 1 | <1% |
Sweden | 1 | <1% |
Spain | 1 | <1% |
Denmark | 1 | <1% |
Unknown | 163 | 94% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Bachelor | 30 | 17% |
Student > Ph. D. Student | 25 | 14% |
Researcher | 23 | 13% |
Student > Master | 23 | 13% |
Other | 12 | 7% |
Other | 38 | 22% |
Unknown | 22 | 13% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 69 | 40% |
Agricultural and Biological Sciences | 20 | 12% |
Biochemistry, Genetics and Molecular Biology | 16 | 9% |
Immunology and Microbiology | 14 | 8% |
Nursing and Health Professions | 8 | 5% |
Other | 21 | 12% |
Unknown | 25 | 14% |