Title |
Micrographia induced by pallidal DBS for segmental dystonia: a subtle sign of hypokinesia?
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Published in |
Journal of Neural Transmission, January 2011
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DOI | 10.1007/s00702-010-0544-y |
Pubmed ID | |
Authors |
Christian Blahak, Hans-Holger Capelle, Hansjoerg Baezner, Thomas M. Kinfe, Michael G. Hennerici, Joachim K. Krauss |
Abstract |
Recently parkinsonism has been reported as a rare side effect of globus pallidus internus (GPi) deep brain stimulation (DBS) for dystonia. In the present systematic prospective study in 11 patients with segmental dystonia not affecting distal arm function, we could demonstrate significant changes in handwriting characterized by mild micrographia following GPi-DBS. We propose that this finding reflects GPi-DBS-induced disturbances of basal ganglia function in terms of a mild hypokinetic syndrome, as a result of outflow alterations in pallido-thalamo-cortical pathways. |
Mendeley readers
The data shown below were compiled from readership statistics for 36 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 1 | 3% |
Netherlands | 1 | 3% |
Italy | 1 | 3% |
Unknown | 33 | 92% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 5 | 14% |
Other | 4 | 11% |
Researcher | 4 | 11% |
Student > Master | 3 | 8% |
Student > Bachelor | 2 | 6% |
Other | 4 | 11% |
Unknown | 14 | 39% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 10 | 28% |
Neuroscience | 7 | 19% |
Linguistics | 1 | 3% |
Social Sciences | 1 | 3% |
Nursing and Health Professions | 1 | 3% |
Other | 2 | 6% |
Unknown | 14 | 39% |