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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Antibiotic Resistance in Enterobacteriaceae from Surface Waters in Urban Brazil Highlights the Risks of Poor Sanitation.
|
|---|---|
| Published in |
The American Journal of Tropical Medicine and Hygiene, June 2019
|
| DOI | 10.4269/ajtmh.18-0726 |
| Pubmed ID | |
| Authors |
Patricia S Bartley, T Nicholas Domitrovic, Vanessa T Moretto, Cleiton S Santos, Rafael Ponce-Terashima, Mitermayer G Reis, Lucio M Barbosa, Ronald E Blanton, Robert A Bonomo, Federico Perez |
| Abstract |
Surface waters are an unappreciated reservoir of antimicrobial resistance (AMR). Poor sanitation brings different species of environmental bacteria into contact, facilitating horizontal gene transfer. To investigate the role of surface waters as potential reservoirs of AMR, we studied the point prevalence of fecal contamination, AMR genes, and Enterobacteriaceae in an urban lake and rural river system in Northeast Brazil in comparison with a lake and sewer system in Northeast Ohio in the United States. Surface water samples were examined for evidence of human fecal contamination using microbial source tracking and screened for plasmid-mediated fluoroquinolone resistance and carbapenemase genes. Enterobacteriaceae were detected using selective agar followed by antimicrobial susceptibility testing and detection of AMR genes by microarray, and classified by repetitive sequence-based PCR and multilocus sequence typing. Concentrations of human fecal bacteria in the Brazilian urban lake and sewage in Northeast Ohio were similarly high. Filtered water samples from the Brazilian urban lake, however, showed the presence of blaOXA-48, blaKPC, blaVIM-2, qnrS, and aac(6')-lb-cr, whereas only blaVIM-2 was identified in raw sewage from Northeast Ohio. From the Brazilian urban lake, 85% of the Enterobacteriaceae (n = 40) cultured were resistant to at least one clinically important antibiotic, including ST131 Escherichia coli harboring the extended-spectrum beta-lactamase CTX-M. Although two isolates demonstrated polymyxin resistance, mcr-1/2 was not detected. Our findings indicate that surface waters in an urban Brazilian site can serve as an environmental reservoir of AMR and that improving wastewater treatment and sanitation generally may ameliorate AMR dissemination. |
X Demographics
The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 2 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 50% |
| Scientists | 1 | 50% |
Mendeley readers
The data shown below were compiled from readership statistics for 135 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 135 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 20 | 15% |
| Student > Master | 17 | 13% |
| Student > Bachelor | 14 | 10% |
| Student > Ph. D. Student | 10 | 7% |
| Student > Doctoral Student | 8 | 6% |
| Other | 23 | 17% |
| Unknown | 43 | 32% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 17 | 13% |
| Immunology and Microbiology | 17 | 13% |
| Medicine and Dentistry | 11 | 8% |
| Environmental Science | 11 | 8% |
| Agricultural and Biological Sciences | 6 | 4% |
| Other | 18 | 13% |
| Unknown | 55 | 41% |
Attention Score in Context
This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 08 June 2019.
All research outputs
#16,990,347
of 25,746,891 outputs
Outputs from The American Journal of Tropical Medicine and Hygiene
#7,479
of 9,579 outputs
Outputs of similar age
#221,137
of 364,946 outputs
Outputs of similar age from The American Journal of Tropical Medicine and Hygiene
#69
of 113 outputs
Altmetric has tracked 25,746,891 research outputs across all sources so far. This one is in the 31st percentile – i.e., 31% of other outputs scored the same or lower than it.
So far Altmetric has tracked 9,579 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.6. This one is in the 20th percentile – i.e., 20% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 364,946 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 36th percentile – i.e., 36% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 113 others from the same source and published within six weeks on either side of this one. This one is in the 35th percentile – i.e., 35% of its contemporaries scored the same or lower than it.