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X Demographics
Mendeley readers
Attention Score in Context
| Title |
HOXD-AS1: a novel oncogenic long intergenic non-coding RNA in humans.
|
|---|---|
| Published in |
European review for medical and pharmacological sciences [Eur Rev Med Pharmacol Sci] NLMUID: 9717360, April 2019
|
| DOI | 10.26355/eurrev_201904_17568 |
| Pubmed ID | |
| Authors |
S C Xie, Y J Yang, J Q Zhang, S Zhou, S W Xie, Y Y Hua |
| Abstract |
Long non-coding RNAs are an emerging special class of regulatory RNAs with more than 200 nucleotides that play vital roles in gene regulation, metabolism, drug resistance, cell differentiation, and other processes. These RNAs were also reported to be dysregulated in human disease, especially malignant tumors. However, the underlying mechanisms remain elusive. HOXD cluster antisense RNA 1 (HOXD-AS1), a recently discovered long non-coding RNA, is overexpressed in many cancers. We now review recent advances in understanding the function, role, regulation, and oncogenic properties of HOXD-AS1. A systematic literature review in PubMed of HOXD-AS1 and cancer-related articles in English, published until June 2018, was conducted. The literature suggests that HOXD-AS1 is an oncogene that regulates diverse physiological and cellular processes such as proliferation, apoptosis, migration, invasion, metastasis, chemoresistance, epithelial to mesenchymal transition, and stem cell formation by interacting with various regulatory proteins and sequestering several microRNAs such as miR-608, miR-130a, and miR-217. HOXD-AS1 may be a prognostic biomarker and potential therapeutic target for various tumor diagnosis and treatment. |
X Demographics
The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 1 | 50% |
| United States | 1 | 50% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Science communicators (journalists, bloggers, editors) | 1 | 50% |
| Members of the public | 1 | 50% |
Mendeley readers
The data shown below were compiled from readership statistics for 19 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 19 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 5 | 26% |
| Student > Ph. D. Student | 3 | 16% |
| Student > Doctoral Student | 1 | 5% |
| Lecturer | 1 | 5% |
| Unspecified | 1 | 5% |
| Other | 4 | 21% |
| Unknown | 4 | 21% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 8 | 42% |
| Biochemistry, Genetics and Molecular Biology | 3 | 16% |
| Arts and Humanities | 1 | 5% |
| Unspecified | 1 | 5% |
| Social Sciences | 1 | 5% |
| Other | 1 | 5% |
| Unknown | 4 | 21% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 22 April 2019.
All research outputs
#19,954,338
of 25,385,509 outputs
Outputs from European review for medical and pharmacological sciences [Eur Rev Med Pharmacol Sci] NLMUID: 9717360
#1,306
of 3,192 outputs
Outputs of similar age
#264,478
of 364,372 outputs
Outputs of similar age from European review for medical and pharmacological sciences [Eur Rev Med Pharmacol Sci] NLMUID: 9717360
#26
of 81 outputs
Altmetric has tracked 25,385,509 research outputs across all sources so far. This one is in the 18th percentile – i.e., 18% of other outputs scored the same or lower than it.
So far Altmetric has tracked 3,192 research outputs from this source. They receive a mean Attention Score of 3.8. This one has gotten more attention than average, scoring higher than 55% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 364,372 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 23rd percentile – i.e., 23% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 81 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 60% of its contemporaries.