Title |
Arnica montana gel in osteoarthritis of the knee: An open, multicenter clinical trial
|
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Published in |
Advances in Therapy, September 2002
|
DOI | 10.1007/bf02850361 |
Pubmed ID | |
Authors |
Otto Knuesel, Michel Weber, Andy Suter |
Abstract |
This open multicenter trial investigated the safety and efficacy of an Arnica montana fresh plant gel, applied twice daily, in 26 men and 53 women with mild to moderate osteoarthritis (OA) of the knee. After 3 and 6 weeks, significant decreases in median total scores on the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC) were evident in the intention-to-treat and per-protocol populations (both P < .0001). Scores on the pain, stiffness, and function subscales also showed significant reductions at these timepoints. The overall local adverse-event rate of 7.6% included only one allergic reaction. Sixty-nine patients (87%) rated the tolerability of the gel as "good" or "fairly good," and 76% would use it again. Topical application of Arnica montana gel for 6 weeks was a safe, well-tolerated, and effective treatment of mild to moderate OA of the knee. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 1 | 20% |
India | 1 | 20% |
Spain | 1 | 20% |
Unknown | 2 | 40% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 4 | 80% |
Practitioners (doctors, other healthcare professionals) | 1 | 20% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United Kingdom | 1 | 1% |
Unknown | 76 | 99% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Bachelor | 13 | 17% |
Student > Master | 11 | 14% |
Researcher | 9 | 12% |
Other | 5 | 6% |
Student > Postgraduate | 5 | 6% |
Other | 14 | 18% |
Unknown | 20 | 26% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 22 | 29% |
Pharmacology, Toxicology and Pharmaceutical Science | 10 | 13% |
Agricultural and Biological Sciences | 9 | 12% |
Nursing and Health Professions | 4 | 5% |
Biochemistry, Genetics and Molecular Biology | 2 | 3% |
Other | 6 | 8% |
Unknown | 24 | 31% |