Non-Natural Nucleic Acids

Chapter 1 Synthesis and Enzymatic Characterization of Sugar-Modified Nucleoside Triphosphate Analogs

Chapter 2 Synthesis of Site-Specific Crown Ether Adducts to DNA Abasic Sites: 8-Oxo-7,8-Dihydro-2′-Deoxyguanosine and 2′-Deoxycytidine

Chapter 3 Synthesis of a Fluorescent Cytidine TNA Triphosphate Analogue

Chapter 4 Synthesis of Base-Modified dNTPs Through Cross-Coupling Reactions and Their Polymerase Incorporation to DNA

Chapter 6 Synthesis Protocols for Simple Uncharged Glycol Carbamate Nucleic Acids

Chapter 8 Synthesis and Application of L KγT Peptide Nucleic Acids

Chapter 10 Preparation and Purification of Oligodeoxynucleotide Duplexes Containing a Site-Specific, Reduced, Chemically Stable Covalent Interstrand Cross-Link Between a Guanine Residue and an Abasic Site

Chapter 11 Copper-Catalyzed Alkyne-Azide Cycloaddition on the Solid Phase for the Preparation of Fully Click-Modified Nucleic Acids

Chapter 12 Labeling Peptide Nucleic Acids with Indium-111

Chapter 13 Site-Specific Labeling of DNA via PCR with an Expanded Genetic Alphabet

Chapter 15 Artificial Nucleosides as Diagnostic Probes to Measure Translesion DNA Synthesis

Chapter 17 The Use of Serinol Nucleic Acids as Ultrasensitive Molecular Beacons

Chapter 18 Oligonucleotide Primers with G 8AE -Clamp Modifications for RT-qPCR Detection of the Low-Copy dsRNA

Chapter 19 Determining Steady-State Kinetics of DNA Polymerase Nucleotide Incorporation