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Two Years Follow up of Domain Specific Cognitive Training in Relapsing Remitting Multiple Sclerosis: A Randomized Clinical Trial

Overview of attention for article published in Frontiers in Behavioral Neuroscience, February 2016
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  • Good Attention Score compared to outputs of the same age (71st percentile)
  • Good Attention Score compared to outputs of the same age and source (70th percentile)

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Title
Two Years Follow up of Domain Specific Cognitive Training in Relapsing Remitting Multiple Sclerosis: A Randomized Clinical Trial
Published in
Frontiers in Behavioral Neuroscience, February 2016
DOI 10.3389/fnbeh.2016.00028
Pubmed ID
Authors

Flavia Mattioli, Fabio Bellomi, Chiara Stampatori, Leandro Provinciali, Laura Compagnucci, Antonio Uccelli, Matteo Pardini, Giuseppe Santuccio, Giuditta Fregonese, Marianna Pattini, Beatrice Allegri, Raffaella Clerici, Annalisa Lattuada, Cristina Montomoli, Barbara Corso, Paolo Gallo, Alice Riccardi, Angelo Ghezzi, Marco Roscio, Maria Rosaria Tola, Chiara Calanca, Daria Baldini, Debora Trafficante, Ruggero Capra

Abstract

Cognitive rehabilitation in multiple sclerosis (MS) has been reported to induce neuropsychological improvements, but the persistence of these effects has been scarcely investigated over long follow ups. Here, the results of a multicenter randomized clinical trial are reported, in which the efficacy of 15 week domain specific cognitive training was evaluated at 2 years follow up in 41 patients. Included patients were randomly assigned either to domain specific cognitive rehabilitation, or to aspecific psychological intervention. Patients who still resulted to be cognitively impaired at 1 year follow up were resubmitted to the same treatment, whereas the recovered ones were not. Neuropsychological tests and functional scales were administered at 2 years follow up to all the patients. Results revealed that both at 1 and at 2 years follow up more patients in the aspecific group (18/19, 94% and 13/17, 76% respectively) than in the specific group (11/22, 50% and 5/15, 33% respectively) resulted to be cognitively impaired. Furthermore patients belonging to the specific group showed significantly less impaired tests compared with the aspecific group ones (p = 0.02) and a significant amelioration in the majority of the tests. On the contrary patients in the aspecific group did not change. The specific group subjects also perceived a subjective improvement in their cognitive performance, while the aspecific group patients did not. These results showed that short time domain specific cognitive rehabilitation is a useful treatment for patients with MS, shows very long lasting effects, compared to aspecific psychological interventions. Also subjective cognitive amelioration was found in patients submitted to domain specific treatment after 2 years.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 80 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 80 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 16 20%
Student > Master 11 14%
Student > Ph. D. Student 9 11%
Student > Bachelor 5 6%
Other 5 6%
Other 18 23%
Unknown 16 20%
Readers by discipline Count As %
Psychology 28 35%
Neuroscience 13 16%
Medicine and Dentistry 8 10%
Nursing and Health Professions 4 5%
Unspecified 4 5%
Other 4 5%
Unknown 19 24%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 5. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 02 October 2020.
All research outputs
#6,114,417
of 22,851,489 outputs
Outputs from Frontiers in Behavioral Neuroscience
#949
of 3,178 outputs
Outputs of similar age
#84,997
of 298,745 outputs
Outputs of similar age from Frontiers in Behavioral Neuroscience
#23
of 80 outputs
Altmetric has tracked 22,851,489 research outputs across all sources so far. This one has received more attention than most of these and is in the 73rd percentile.
So far Altmetric has tracked 3,178 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 11.4. This one has gotten more attention than average, scoring higher than 69% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 298,745 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 71% of its contemporaries.
We're also able to compare this research output to 80 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 70% of its contemporaries.