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Krüppeling erythropoiesis: an unexpected broad spectrum of human red blood cell disorders due to KLF1 variants

Overview of attention for article published in Blood, February 2016
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (81st percentile)
  • Good Attention Score compared to outputs of the same age and source (69th percentile)

Mentioned by

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13 X users
wikipedia
1 Wikipedia page

Citations

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133 Dimensions

Readers on

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79 Mendeley
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Title
Krüppeling erythropoiesis: an unexpected broad spectrum of human red blood cell disorders due to KLF1 variants
Published in
Blood, February 2016
DOI 10.1182/blood-2016-01-694331
Pubmed ID
Authors

Andrew Perkins, Xiangmin Xu, Douglas R. Higgs, George P. Patrinos, Lionel Arnaud, James J. Bieker, Sjaak Philipsen, the KLF1 Consensus Workgroup

Abstract

Until recently our approach to the analysis of human genetic diseases has been to accurately phenotype patients and sequence the genes known to be associated with those phenotypes; for example, analysing the globin loci in cases of thalassemia. As sequencing has become increasingly accessible, a larger panel of genes is now analysed and whole exome/genome sequencing is applied in cases where no variants are found in the candidate genes. Using such approaches in patients with unexplained anemias, we have discovered that a broad range of hitherto unrelated human red cell disorders are caused by variants in KLF1, a master regulator of erythropoiesis, previously considered to be extremely rare causes of human genetic disease.

X Demographics

X Demographics

The data shown below were collected from the profiles of 13 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 79 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 1%
Japan 1 1%
United States 1 1%
Canada 1 1%
Unknown 75 95%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 16 20%
Researcher 11 14%
Student > Master 9 11%
Student > Postgraduate 7 9%
Other 6 8%
Other 19 24%
Unknown 11 14%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 33 42%
Medicine and Dentistry 14 18%
Agricultural and Biological Sciences 13 16%
Immunology and Microbiology 3 4%
Nursing and Health Professions 2 3%
Other 4 5%
Unknown 10 13%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 10. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 17 December 2023.
All research outputs
#3,735,453
of 25,503,365 outputs
Outputs from Blood
#4,813
of 33,372 outputs
Outputs of similar age
#56,642
of 313,218 outputs
Outputs of similar age from Blood
#83
of 274 outputs
Altmetric has tracked 25,503,365 research outputs across all sources so far. Compared to these this one has done well and is in the 85th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 33,372 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 7.6. This one has done well, scoring higher than 85% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 313,218 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 81% of its contemporaries.
We're also able to compare this research output to 274 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 69% of its contemporaries.