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Can Molecular Gradients Wire the Brain?

Overview of attention for article published in Trends in Neurosciences, February 2016
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About this Attention Score

  • Good Attention Score compared to outputs of the same age (69th percentile)

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Title
Can Molecular Gradients Wire the Brain?
Published in
Trends in Neurosciences, February 2016
DOI 10.1016/j.tins.2016.01.009
Pubmed ID
Authors

Geoffrey J. Goodhill

Abstract

Concentration gradients are believed to play a key role in guiding axons to their appropriate targets during neural development. However, there are fundamental physical constraints on gradient detection, and these strongly limit the fidelity with which axons can respond to gradient cues. I discuss these constraints and argue they suggest that many axon guidance events in vivo cannot be explained solely in terms of gradient-based mechanisms. Rather, precise wiring requires the collaboration of gradients with other types of guidance cues. Since we know relatively little about how this might work, I argue that our understanding of how the brain becomes wired up during development is still at an early stage.

X Demographics

X Demographics

The data shown below were collected from the profiles of 5 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 111 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 2 2%
United States 1 <1%
Switzerland 1 <1%
Unknown 107 96%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 32 29%
Researcher 25 23%
Student > Bachelor 13 12%
Student > Master 7 6%
Professor > Associate Professor 5 5%
Other 16 14%
Unknown 13 12%
Readers by discipline Count As %
Agricultural and Biological Sciences 29 26%
Neuroscience 28 25%
Medicine and Dentistry 9 8%
Biochemistry, Genetics and Molecular Biology 7 6%
Physics and Astronomy 7 6%
Other 15 14%
Unknown 16 14%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 5. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 28 May 2021.
All research outputs
#7,204,882
of 25,373,627 outputs
Outputs from Trends in Neurosciences
#1,339
of 2,484 outputs
Outputs of similar age
#93,521
of 311,887 outputs
Outputs of similar age from Trends in Neurosciences
#18
of 22 outputs
Altmetric has tracked 25,373,627 research outputs across all sources so far. This one has received more attention than most of these and is in the 71st percentile.
So far Altmetric has tracked 2,484 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 18.0. This one is in the 45th percentile – i.e., 45% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 311,887 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 69% of its contemporaries.
We're also able to compare this research output to 22 others from the same source and published within six weeks on either side of this one. This one is in the 18th percentile – i.e., 18% of its contemporaries scored the same or lower than it.