| Title |
The sexually dimorphic impact of maltreatment on cortical thickness, surface area and gyrification
|
|---|---|
| Published in |
Journal of Neural Transmission, February 2016
|
| DOI | 10.1007/s00702-016-1523-8 |
| Pubmed ID | |
| Authors |
Philip A. Kelly, Essi Viding, Vanessa B. Puetz, Amy L. Palmer, Sophie Samuel, Eamon J. McCrory |
| Abstract |
An extensive literature has detailed how maltreatment experience impacts brain structure in children and adolescents. However, there is a dearth of studies on the influence of maltreatment on surface based indices, and to date no study has investigated how sex influences the impact of maltreatment on cortical thickness, surface area and local gyrification. We investigated sex differences in these measures of cortical structure in a large community sample of children aged 10-14 years (n = 122) comprising 62 children with verified maltreatment experience and 60 matched non-maltreated controls. The maltreated group relative to the controls presented with a pattern of decreased cortical thickness within a region of right anterior cingulate, orbitofrontal cortex and superior frontal gyrus; decreased surface area within the right inferior parietal cortex; and increased local gyrification within left superior parietal cortex. This atypical pattern of cortical structure was similar across males and females. An interaction between maltreatment exposure and sex was found only in local gyrification, within two clusters: the right tempo-parietal junction and the left precentral gyrus. These findings suggest that maltreatment impacts cortical structure in brain areas associated with emotional regulation and theory of mind, with few differences between the sexes. |
X Demographics
The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 1 | 33% |
| United States | 1 | 33% |
| Unknown | 1 | 33% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Scientists | 2 | 67% |
| Practitioners (doctors, other healthcare professionals) | 1 | 33% |
Mendeley readers
The data shown below were compiled from readership statistics for 100 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 100 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Master | 19 | 19% |
| Student > Bachelor | 12 | 12% |
| Student > Doctoral Student | 11 | 11% |
| Student > Ph. D. Student | 11 | 11% |
| Researcher | 10 | 10% |
| Other | 10 | 10% |
| Unknown | 27 | 27% |
| Readers by discipline | Count | As % |
|---|---|---|
| Psychology | 28 | 28% |
| Neuroscience | 11 | 11% |
| Medicine and Dentistry | 10 | 10% |
| Social Sciences | 8 | 8% |
| Agricultural and Biological Sciences | 3 | 3% |
| Other | 5 | 5% |
| Unknown | 35 | 35% |
Attention Score in Context
This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 07 March 2016.
All research outputs
#14,839,922
of 22,852,911 outputs
Outputs from Journal of Neural Transmission
#1,202
of 1,768 outputs
Outputs of similar age
#166,781
of 297,543 outputs
Outputs of similar age from Journal of Neural Transmission
#12
of 25 outputs
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We're also able to compare this research output to 25 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 52% of its contemporaries.