Title |
Transdermal drug delivery: Basic principles for the veterinarian
|
---|---|
Published in |
Veterinary Journal, December 2005
|
DOI | 10.1016/j.tvjl.2005.09.006 |
Pubmed ID | |
Authors |
P.C. Mills, S.E. Cross |
Abstract |
The use of topical pharmaceutical formulations is increasingly popular in veterinary medicine. A potential concern is that not all formulations are registered for the intended species, yet current knowledge strongly suggests that simple extrapolation of transdermal drug pharmacokinetics and pharmacodynamics between species, including humans, cannot be done. In this review, an overview is provided of the underlying basic principles determining the movement of topically applied molecules into and through the skin. Various factors that may affect transdermal drug penetration between species, between individuals of a particular species and regional differences in an individual are also discussed. A good understanding of the basic principles of transdermal drug delivery is critical to avoid adverse effects or lack of efficacy when applying topical formulations in veterinary medicine. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Germany | 1 | 1% |
Malaysia | 1 | 1% |
Brazil | 1 | 1% |
United Kingdom | 1 | 1% |
Mexico | 1 | 1% |
Belgium | 1 | 1% |
Unknown | 89 | 94% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 22 | 23% |
Researcher | 19 | 20% |
Student > Master | 10 | 11% |
Professor > Associate Professor | 6 | 6% |
Student > Doctoral Student | 5 | 5% |
Other | 20 | 21% |
Unknown | 13 | 14% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 26 | 27% |
Agricultural and Biological Sciences | 15 | 16% |
Pharmacology, Toxicology and Pharmaceutical Science | 10 | 11% |
Chemistry | 7 | 7% |
Engineering | 6 | 6% |
Other | 12 | 13% |
Unknown | 19 | 20% |