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Biofilm’s Role in Chronic Cholesteatomatous Otitis Media

Overview of attention for article published in Otolaryngology–Head and Neck Surgery, March 2016
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  • In the top 25% of all research outputs scored by Altmetric
  • Good Attention Score compared to outputs of the same age (78th percentile)
  • High Attention Score compared to outputs of the same age and source (88th percentile)

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Title
Biofilm’s Role in Chronic Cholesteatomatous Otitis Media
Published in
Otolaryngology–Head and Neck Surgery, March 2016
DOI 10.1177/0194599816630548
Pubmed ID
Authors

Jacopo Galli, Lea Calò, Monica Giuliani, Bruno Sergi, Daniela Lucidi, Duino Meucci, Ezio Bassotti, Maurizio Sanguinetti, Gaetano Paludetti

Abstract

Cholesteatoma is a destructive lesion involving the temporal bone, which may induce severe complications due to its expansion and erosion of adjacent structures. Bacterial biofilm plays a crucial role in the pathogenesis of many otolaryngologic inflammatory/infectious chronic diseases. In this pilot study, we investigated, by means of cultural examination and with scanning electron microscope, the presence of bacterial biofilm in a series of samples from the epitympanic and mastoid region in patients affected by cholesteatoma and from the promontory region in patients with healthy mucosa who were undergoing to stapes surgery. The preliminary data support the association between biofilm and cholesteatoma (81.3% of the cases) and allow us to hypothesize that keratinized matrix of cholesteatoma may represent the ideal substrate for biofilm colonization and survival; this finding is consistent with the clinical course of aural cholesteatoma, characterized by recurrent exacerbations and recalcitrant course.

X Demographics

X Demographics

The data shown below were collected from the profiles of 14 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 25 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 25 100%

Demographic breakdown

Readers by professional status Count As %
Student > Postgraduate 4 16%
Student > Master 4 16%
Student > Bachelor 2 8%
Professor 2 8%
Student > Doctoral Student 1 4%
Other 5 20%
Unknown 7 28%
Readers by discipline Count As %
Medicine and Dentistry 11 44%
Biochemistry, Genetics and Molecular Biology 3 12%
Unspecified 1 4%
Immunology and Microbiology 1 4%
Agricultural and Biological Sciences 1 4%
Other 0 0%
Unknown 8 32%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 8. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 14 March 2016.
All research outputs
#4,608,356
of 25,377,790 outputs
Outputs from Otolaryngology–Head and Neck Surgery
#509
of 4,086 outputs
Outputs of similar age
#65,665
of 312,604 outputs
Outputs of similar age from Otolaryngology–Head and Neck Surgery
#10
of 88 outputs
Altmetric has tracked 25,377,790 research outputs across all sources so far. Compared to these this one has done well and is in the 81st percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 4,086 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 7.2. This one has done well, scoring higher than 87% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 312,604 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 78% of its contemporaries.
We're also able to compare this research output to 88 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 88% of its contemporaries.