Title |
Infection in cystic fibrosis: impact of the environment and climate
|
---|---|
Published in |
Expert Review of Respiratory Medicine, March 2016
|
DOI | 10.1586/17476348.2016.1162715 |
Pubmed ID | |
Authors |
KA Ramsay, RE Stockwell, SC Bell, TJ Kidd |
Abstract |
In many countries numbers of adults with cystic fibrosis (CF) exceed that of children, with median survival predicted to surpass 50 years. Increasing longevity is, in part, due to intensive therapies including eradication of early infection and suppressive therapies and pulmonary exacerbations. Initial infections with common CF pathogens are thought to arise from the natural environment. We review the impact of climate and environment on infection in CF Specifically, several studies indicate that higher ambient temperatures, proximity to the equator and the summer season may be linked to the increased prevalence of P. aeruginosa in people with CF. The environment may also play an important role in the acquisition of Gram negative organisms other than P. aeruginosa. There is emerging data suggesting that climatic and environmental factors are likely to impact on the risk of infection with NTM and fungi in people which are found extensively throughout the natural environment. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Australia | 1 | 13% |
Unknown | 7 | 88% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 7 | 88% |
Practitioners (doctors, other healthcare professionals) | 1 | 13% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 49 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 8 | 16% |
Student > Master | 5 | 10% |
Student > Bachelor | 4 | 8% |
Other | 4 | 8% |
Student > Doctoral Student | 3 | 6% |
Other | 9 | 18% |
Unknown | 16 | 33% |
Readers by discipline | Count | As % |
---|---|---|
Immunology and Microbiology | 10 | 20% |
Medicine and Dentistry | 6 | 12% |
Biochemistry, Genetics and Molecular Biology | 4 | 8% |
Agricultural and Biological Sciences | 3 | 6% |
Nursing and Health Professions | 2 | 4% |
Other | 7 | 14% |
Unknown | 17 | 35% |