| Title |
Tumor-associated macrophages and anti-tumor therapies: complex links
|
|---|---|
| Published in |
Cellular and Molecular Life Sciences, March 2016
|
| DOI | 10.1007/s00018-016-2166-5 |
| Pubmed ID | |
| Authors |
Cristina Belgiovine, Maurizio D’Incalci, Paola Allavena, Roberta Frapolli |
| Abstract |
Myeloid cells infiltrating the tumor microenvironment, especially tumor-associated macrophages (TAMs), are essential providers of cancer-related inflammation, a condition known to accelerate tumor progression and limit the response to anti-tumor therapies. As a matter of fact, TAMs may have a dual role while interfering with cancer treatments, as they can either promote or impair their functionality. Here we review the connection between macrophages and anticancer therapies; moreover, we provide an overview of the different strategies to target or re-program TAMs for therapeutic purposes. |
Mendeley readers
The data shown below were compiled from readership statistics for 110 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 1 | <1% |
| Unknown | 109 | 99% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 22 | 20% |
| Student > Master | 19 | 17% |
| Researcher | 14 | 13% |
| Student > Bachelor | 9 | 8% |
| Student > Doctoral Student | 8 | 7% |
| Other | 9 | 8% |
| Unknown | 29 | 26% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 20 | 18% |
| Medicine and Dentistry | 18 | 16% |
| Immunology and Microbiology | 16 | 15% |
| Agricultural and Biological Sciences | 11 | 10% |
| Engineering | 4 | 4% |
| Other | 8 | 7% |
| Unknown | 33 | 30% |
Attention Score in Context
This research output has an Altmetric Attention Score of 6. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 03 November 2016.
All research outputs
#6,047,762
of 23,794,258 outputs
Outputs from Cellular and Molecular Life Sciences
#1,285
of 4,151 outputs
Outputs of similar age
#81,902
of 301,159 outputs
Outputs of similar age from Cellular and Molecular Life Sciences
#22
of 69 outputs
Altmetric has tracked 23,794,258 research outputs across all sources so far. This one has received more attention than most of these and is in the 74th percentile.
So far Altmetric has tracked 4,151 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.0. This one has gotten more attention than average, scoring higher than 68% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 301,159 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 72% of its contemporaries.
We're also able to compare this research output to 69 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 66% of its contemporaries.