| Title |
Interspecies transmission of prions
|
|---|---|
| Published in |
Biochemistry, January 2012
|
| DOI | 10.1134/s0006297911130013 |
| Pubmed ID | |
| Authors |
E. G. Afanasieva, V. V. Kushnirov, M. D. Ter-Avanesyan |
| Abstract |
Mammalian prions are infectious agents of proteinaceous nature that cause several incurable neurodegenerative diseases. Interspecies transmission of prions is usually impeded or impossible. Barriers in prion transmission are caused by small interspecies differences in the primary structure of prion proteins. The barriers can also depend on the strain (variant) of a transmitted prion. Interspecies barriers were also shown for yeast prions, which define some heritable phenotypes. Yeast prions reproduce all the main traits of prion transmission barriers observed for mammals. This allowed to show that the barrier in prion transmission can be observed even upon copolymerization of two prionogenic proteins. Available data allow elucidation of the mechanisms that impede prion transmission or make it impossible. |
X Demographics
The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Mexico | 1 | 50% |
| Unknown | 1 | 50% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 2 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 36 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Canada | 2 | 6% |
| Brazil | 1 | 3% |
| France | 1 | 3% |
| Israel | 1 | 3% |
| Russia | 1 | 3% |
| Unknown | 30 | 83% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 12 | 33% |
| Student > Ph. D. Student | 9 | 25% |
| Student > Bachelor | 4 | 11% |
| Student > Master | 3 | 8% |
| Other | 2 | 6% |
| Other | 4 | 11% |
| Unknown | 2 | 6% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 18 | 50% |
| Biochemistry, Genetics and Molecular Biology | 8 | 22% |
| Medicine and Dentistry | 3 | 8% |
| Veterinary Science and Veterinary Medicine | 2 | 6% |
| Immunology and Microbiology | 2 | 6% |
| Other | 1 | 3% |
| Unknown | 2 | 6% |
Attention Score in Context
This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 24 February 2012.
All research outputs
#16,578,616
of 25,368,786 outputs
Outputs from Biochemistry
#19,277
of 22,288 outputs
Outputs of similar age
#165,012
of 247,179 outputs
Outputs of similar age from Biochemistry
#50
of 78 outputs
Altmetric has tracked 25,368,786 research outputs across all sources so far. This one is in the 34th percentile – i.e., 34% of other outputs scored the same or lower than it.
So far Altmetric has tracked 22,288 research outputs from this source. They receive a mean Attention Score of 4.4. This one is in the 13th percentile – i.e., 13% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 247,179 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 32nd percentile – i.e., 32% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 78 others from the same source and published within six weeks on either side of this one. This one is in the 34th percentile – i.e., 34% of its contemporaries scored the same or lower than it.