Title |
Mitral Valve Perforation in Libman–Sacks Endocarditis: A Heart-Wrenching Case of Lupus
|
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Published in |
Journal of General Internal Medicine, March 2016
|
DOI | 10.1007/s11606-016-3640-3 |
Pubmed ID | |
Authors |
Elizabeth S. Aby, Zachary Rosol, Mengistu A. Simegn |
Abstract |
Libman-Sacks (LS) endocarditis is one of the most common cardiac manifestations of systemic lupus erythematosus. Rarely, however, it can lead to serious complications, including severe valvular regurgitation or superimposed bacterial endocarditis. We describe the initial diagnostic challenges, clinical course, imaging studies and histopathological findings of a patient who presented with life-threatening lupus complicated by hemoptysis and respiratory failure secondary to a rare complication of LS endocarditis, acute mitral valve perforation. We review the current literature on valve perforation in the setting of LS endocarditis. In conclusion, although the disease is often asymptomatic and hemodynamically insignificant, it can result in serious and potentially fatal complications secondary to valve perforation, which may demand emergency surgical management. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Science communicators (journalists, bloggers, editors) | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 22 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Bachelor | 4 | 18% |
Researcher | 3 | 14% |
Other | 2 | 9% |
Student > Doctoral Student | 2 | 9% |
Student > Ph. D. Student | 2 | 9% |
Other | 2 | 9% |
Unknown | 7 | 32% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 6 | 27% |
Nursing and Health Professions | 2 | 9% |
Unspecified | 1 | 5% |
Biochemistry, Genetics and Molecular Biology | 1 | 5% |
Psychology | 1 | 5% |
Other | 1 | 5% |
Unknown | 10 | 45% |