Title |
Peptide‐Decorated Dendrimers and Their Bioapplications
|
---|---|
Published in |
Angewandte Chemie. International Edition, March 2016
|
DOI | 10.1002/anie.201508428 |
Pubmed ID | |
Authors |
Jingjing Wan, Paul F. Alewood |
Abstract |
Peptide-decorated dendrimers (PDDs) are a class of spherical, regular, branched polymers that are modified by peptides covalently attached to their surface. PDDs have been used as protein mimetics, novel biomaterials, and in a wide range of biomedical applications. Since their design and development in the late eighties, poly-l-lysine has been a preferred core structure for PDDs. However, numerous recent innovations in polymer synthesis and ligation chemistry have re-energized the field and led to the emergence of well-defined peptide dendrimers with more diverse core structures and functions. This Minireview highlights the development of PDDs driven by significantly improved ligation chemistry incorporating structurally well-defined peptides and the emerging use of PDDs in imaging and drug development. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Germany | 1 | 33% |
France | 1 | 33% |
Unknown | 1 | 33% |
Demographic breakdown
Type | Count | As % |
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Scientists | 3 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 71 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 21 | 30% |
Researcher | 7 | 10% |
Student > Bachelor | 7 | 10% |
Student > Master | 7 | 10% |
Student > Doctoral Student | 6 | 8% |
Other | 12 | 17% |
Unknown | 11 | 15% |
Readers by discipline | Count | As % |
---|---|---|
Chemistry | 35 | 49% |
Materials Science | 7 | 10% |
Biochemistry, Genetics and Molecular Biology | 3 | 4% |
Agricultural and Biological Sciences | 3 | 4% |
Medicine and Dentistry | 3 | 4% |
Other | 5 | 7% |
Unknown | 15 | 21% |