| Title |
Irritable bowel syndrome: is it associated with genotypes of Blastocystis hominis
|
|---|---|
| Published in |
Parasitology Research, February 2010
|
| DOI | 10.1007/s00436-010-1761-x |
| Pubmed ID | |
| Authors |
Javed Yakoob, Wasim Jafri, Mohammad Asim Beg, Zaigham Abbas, Shagufta Naz, Muhammad Islam, Rustam Khan |
| Abstract |
Blastocystis hominis is the most common intestinal parasite in humans. An extensive genetic variability has been described recently in B. hominis isolates. The aim of this study was to analyze genotypes of B. hominis isolates obtained from the healthy individuals and patients with irritable bowel syndrome-diarrhea (IBS-D). The patients with IBS-D were enrolled from gastroenterology outpatient department at the Aga Khan University Hospital. History and physical examination was done. Stool microscopy, culture, and polymerase chain reaction for B. hominis genotyping were carried out. The study included 158 patients with IBS-D, mean age 41 +/- 15, age range 16-83 years, and male/female ratio of 109:49. One hundred fifty-seven (49.8%) were taken as healthy control. The dominant B. hominis genotypes were genotype 1 in 87 (65%) and type 3 in 49 (37%). In IBS-D, genotype 1 was present in 75 (86%; P < 0.001) compared to 12 (14%) in controls while type 3 was present in 23 (47%) compared to 26 (53%) in controls (P < 0.001), respectively. Infection with single genotype of B. hominis was present in 70 (73%) with IBS-D and in 26 (27%) in control group while with multiple genotypes in 25 (64%) in IBS-D and 14 (36%) in control group (P = 0.30), respectively. Majority of our patients had typeable B. hominis infection. The genotype of B. hominis in IBS-D was type 1 while in control genotype 3 was predominant. |
Mendeley readers
The data shown below were compiled from readership statistics for 99 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Australia | 2 | 2% |
| Canada | 1 | 1% |
| United States | 1 | 1% |
| Unknown | 95 | 96% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 19 | 19% |
| Student > Master | 15 | 15% |
| Student > Ph. D. Student | 12 | 12% |
| Researcher | 11 | 11% |
| Lecturer | 5 | 5% |
| Other | 20 | 20% |
| Unknown | 17 | 17% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 37 | 37% |
| Agricultural and Biological Sciences | 14 | 14% |
| Immunology and Microbiology | 9 | 9% |
| Biochemistry, Genetics and Molecular Biology | 7 | 7% |
| Veterinary Science and Veterinary Medicine | 4 | 4% |
| Other | 11 | 11% |
| Unknown | 17 | 17% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 20 February 2012.
All research outputs
#20,155,513
of 22,663,150 outputs
Outputs from Parasitology Research
#2,863
of 3,767 outputs
Outputs of similar age
#89,343
of 93,601 outputs
Outputs of similar age from Parasitology Research
#19
of 20 outputs
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We're also able to compare this research output to 20 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.