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Incidence and risk factors for clozapine-induced myocarditis and cardiomyopathy at a regional mental health service in Australia

Overview of attention for article published in Australasian Psychiatry, September 2015
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (84th percentile)
  • High Attention Score compared to outputs of the same age and source (92nd percentile)

Mentioned by

news
1 news outlet
policy
1 policy source
facebook
1 Facebook page

Citations

dimensions_citation
47 Dimensions

Readers on

mendeley
39 Mendeley
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Title
Incidence and risk factors for clozapine-induced myocarditis and cardiomyopathy at a regional mental health service in Australia
Published in
Australasian Psychiatry, September 2015
DOI 10.1177/1039856215604480
Pubmed ID
Authors

Daniel L Youssef, Pradeep Narayanan, Neeraj Gill

Abstract

To determine the incidence of clozapine-induced myocarditis and cardiomyopathy and identify risk factors. A cohort of 129 patients initiated on clozapine at Toowoomba Mental Health Service from year 2000 until 2011 was examined to evaluate cases of myocarditis and cardiomyopathy. Risk factors were analysed using multivariable logistic regression. The incidence of clozapine-induced myocarditis and cardiomyopathy was 3.88% and 4.65% (or 2.26 per 100 patient years), respectively. A significant association was identified between clozapine-induced myocarditis and SSRI use (p = 0.043). Subclinical cardiomyopathy was identified in the absence of symptoms in the majority of cases. These results illustrate a high incidence of clozapine-induced myocarditis as well as cardiomyopathy, reinforcing the need for a standardised, mandatory monitoring scheme. Concomitant SSRI use as one such potential predictor merits further study.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 39 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
New Zealand 1 3%
Unknown 38 97%

Demographic breakdown

Readers by professional status Count As %
Researcher 6 15%
Student > Bachelor 5 13%
Other 4 10%
Professor > Associate Professor 3 8%
Student > Doctoral Student 3 8%
Other 11 28%
Unknown 7 18%
Readers by discipline Count As %
Medicine and Dentistry 12 31%
Pharmacology, Toxicology and Pharmaceutical Science 4 10%
Nursing and Health Professions 4 10%
Psychology 3 8%
Social Sciences 3 8%
Other 5 13%
Unknown 8 21%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 11. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 01 June 2022.
All research outputs
#2,895,088
of 22,925,760 outputs
Outputs from Australasian Psychiatry
#111
of 1,432 outputs
Outputs of similar age
#41,176
of 274,996 outputs
Outputs of similar age from Australasian Psychiatry
#3
of 39 outputs
Altmetric has tracked 22,925,760 research outputs across all sources so far. Compared to these this one has done well and is in the 87th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,432 research outputs from this source. They receive a mean Attention Score of 4.4. This one has done particularly well, scoring higher than 92% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 274,996 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 84% of its contemporaries.
We're also able to compare this research output to 39 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 92% of its contemporaries.