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Placental biomarkers and angiogenic factors in oral fluids of patients with preeclampsia

Overview of attention for article published in Prenatal Diagnosis, April 2016
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (89th percentile)
  • High Attention Score compared to outputs of the same age and source (89th percentile)

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1 news outlet
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1 X user
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4 patents

Citations

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27 Dimensions

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81 Mendeley
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Title
Placental biomarkers and angiogenic factors in oral fluids of patients with preeclampsia
Published in
Prenatal Diagnosis, April 2016
DOI 10.1002/pd.4811
Pubmed ID
Authors

Alejandra Chaparro, Dominique Gaedechens, Valeria Ramírez, Edgardo Zuñiga, Juan Pedro Kusanovic, Carolina Inostroza, Manuel Varas-Godoy, Karla Silva, Carlos Salomon, Gregory Rice, Sebastián Enrique Illanes

Abstract

to explore the feasibility of measuring endothelial and placental biomarkers in saliva and gingival crevicular fluid (GCF), and to determine if patients with PE have a different profile of these biomarkers in oral fluids. Method A case-control study was conducted, including patients with PE (n = 10) and a control group with normal pregnancies randomly selected (n = 20) admitted at the Sótero del Río Hospital in Santiago, Chile. A complete periodontal and obstetric history, involved the collection of oral fluids were performed at the same gestational age. Levels of Cd63+ extracellular-vesicles, placental alkaline phosphatase (PLAP), placental growth factor (PlGF) and sFlt-1 levels were determined by ELISA assays. Data analysis was performed with Chi-square or Fisher's exact test, and Mann-Whitney U test for continuous variables. The association was assessed using a multiple logistic regression model. sFlt-1 concentrations in saliva and GCF were significantly higher in patients with PE (p = 0.045 and p = 0.033 respectively). Concentrations of PLAP were elevated in GCF of PE patients (p = 0.049). The PLAP/CD63+ ratio in GCF of PE patients was significantly higher (p = 0.0008). No differences in PlGF levels were observed. GCF of PE patient's concentrates higher levels of biomarkers related with the PE development. This article is protected by copyright. All rights reserved.

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X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 81 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Colombia 1 1%
Unknown 80 99%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 10 12%
Researcher 10 12%
Student > Master 8 10%
Professor > Associate Professor 6 7%
Student > Doctoral Student 4 5%
Other 16 20%
Unknown 27 33%
Readers by discipline Count As %
Medicine and Dentistry 29 36%
Biochemistry, Genetics and Molecular Biology 9 11%
Agricultural and Biological Sciences 3 4%
Nursing and Health Professions 2 2%
Business, Management and Accounting 2 2%
Other 7 9%
Unknown 29 36%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 19. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 15 June 2021.
All research outputs
#1,958,564
of 25,373,627 outputs
Outputs from Prenatal Diagnosis
#78
of 2,385 outputs
Outputs of similar age
#31,962
of 315,523 outputs
Outputs of similar age from Prenatal Diagnosis
#3
of 39 outputs
Altmetric has tracked 25,373,627 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 92nd percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 2,385 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.2. This one has done particularly well, scoring higher than 96% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 315,523 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 89% of its contemporaries.
We're also able to compare this research output to 39 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 89% of its contemporaries.