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Ferrocene-Modified Phospholipid: An Innovative Precursor for Redox-Triggered Drug Delivery Vesicles Selective to Cancer Cells

Overview of attention for article published in Langmuir, April 2016
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • Good Attention Score compared to outputs of the same age (74th percentile)
  • High Attention Score compared to outputs of the same age and source (87th percentile)

Mentioned by

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4 X users
facebook
1 Facebook page
wikipedia
5 Wikipedia pages
video
1 YouTube creator

Citations

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61 Dimensions

Readers on

mendeley
74 Mendeley
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Title
Ferrocene-Modified Phospholipid: An Innovative Precursor for Redox-Triggered Drug Delivery Vesicles Selective to Cancer Cells
Published in
Langmuir, April 2016
DOI 10.1021/acs.langmuir.6b00511
Pubmed ID
Authors

Tomer Noyhouzer, Chloé L’Homme, Isabelle Beaulieu, Stephanie Mazurkiewicz, Sabine Kuss, Heinz-Bernhard Kraatz, Sylvain Canesi, Janine Mauzeroll

Abstract

Controlled payload release is one of the key elements in the creation of a reliable drug delivery system. We report the discovery of a drug delivery vessel able to transport chemotherapeutic agents to target cancer cells and selectively trigger their release using the electrochemical activity of a ferrocene modified phospholipid. Supported by in vitro assays, the competitive advantages of this discovery are; i) the simple one step scalability of the synthetic process, ii) the stable encapsulation of toxic drugs (doxorubicin) during transport and iii) the selective redox triggering of the liposomes to harness their cytotoxic payload at the cancer site. Specifically the redox modified giant unilamellar vesicle and liposomes were characterized using advanced methods such as Scanning Electrochemical Microscopy (SECM), Transmission Electron Microscopy (TEM), Dynamic Light Scattering (DLS) and fluorescent imaging.

X Demographics

X Demographics

The data shown below were collected from the profiles of 4 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 74 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 74 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 20 27%
Researcher 12 16%
Student > Doctoral Student 6 8%
Student > Bachelor 6 8%
Student > Master 5 7%
Other 9 12%
Unknown 16 22%
Readers by discipline Count As %
Chemistry 33 45%
Biochemistry, Genetics and Molecular Biology 8 11%
Engineering 3 4%
Materials Science 3 4%
Pharmacology, Toxicology and Pharmaceutical Science 2 3%
Other 3 4%
Unknown 22 30%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 6. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 21 May 2023.
All research outputs
#5,463,623
of 22,856,968 outputs
Outputs from Langmuir
#2,816
of 13,970 outputs
Outputs of similar age
#77,199
of 299,468 outputs
Outputs of similar age from Langmuir
#20
of 164 outputs
Altmetric has tracked 22,856,968 research outputs across all sources so far. Compared to these this one has done well and is in the 76th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 13,970 research outputs from this source. They receive a mean Attention Score of 3.8. This one has done well, scoring higher than 79% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 299,468 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 74% of its contemporaries.
We're also able to compare this research output to 164 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 87% of its contemporaries.