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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Non-invasive and label-free detection of oral squamous cell carcinoma using saliva surface-enhanced Raman spectroscopy and multivariate analysis
|
|---|---|
| Published in |
Nanomedicine: Nanotechnology, Biology and Medicine, March 2016
|
| DOI | 10.1016/j.nano.2016.02.021 |
| Pubmed ID | |
| Authors |
Jennifer M. Connolly, Karen Davies, Agne Kazakeviciute, Antony M. Wheatley, Peter Dockery, Ivan Keogh, Malini Olivo |
| Abstract |
Reported here is the application of silver nanoparticle-based surface-enhanced Raman spectroscopy (SERS) as a label-free, non-invasive technique for detection of oral squamous cell cancer (OSCC) using saliva and desquamated oral cells. A total of 180 SERS spectra were acquired from saliva and 120 SERS spectra from oral cells collected from normal healthy individuals and from confirmed oropharyngeal cancer patients. Notable biochemical peaks in the SERS spectra were tentatively assigned to various components. Data were subjected to multivariate statistical techniques including principal component analysis and linear discriminate analysis (PCA-LDA) revealing a sensitivity of 89% and 68% and a diagnostic accuracy of 73% and 60% for saliva and oral cells, respectively. The results from this study demonstrate the potential of saliva and oral cell SERS combined with PCA-LDA diagnostic algorithms as a promising clinical adjunct for the non-invasive detection of oral cancer. |
X Demographics
The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 2 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 2 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 110 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Finland | 1 | <1% |
| United Kingdom | 1 | <1% |
| Unknown | 108 | 98% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 17 | 15% |
| Researcher | 16 | 15% |
| Student > Master | 13 | 12% |
| Student > Doctoral Student | 9 | 8% |
| Student > Bachelor | 9 | 8% |
| Other | 18 | 16% |
| Unknown | 28 | 25% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 12 | 11% |
| Medicine and Dentistry | 11 | 10% |
| Chemistry | 10 | 9% |
| Engineering | 9 | 8% |
| Physics and Astronomy | 8 | 7% |
| Other | 23 | 21% |
| Unknown | 37 | 34% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 19 September 2018.
All research outputs
#19,942,887
of 25,371,288 outputs
Outputs from Nanomedicine: Nanotechnology, Biology and Medicine
#1,044
of 1,520 outputs
Outputs of similar age
#219,585
of 314,783 outputs
Outputs of similar age from Nanomedicine: Nanotechnology, Biology and Medicine
#31
of 67 outputs
Altmetric has tracked 25,371,288 research outputs across all sources so far. This one is in the 18th percentile – i.e., 18% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,520 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.6. This one is in the 27th percentile – i.e., 27% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 314,783 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 25th percentile – i.e., 25% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 67 others from the same source and published within six weeks on either side of this one. This one is in the 37th percentile – i.e., 37% of its contemporaries scored the same or lower than it.