Title |
Practice Update: Review of Anticonvulsant Therapy
|
---|---|
Published in |
Current Neurology and Neuroscience Reports, March 2016
|
DOI | 10.1007/s11910-016-0640-y |
Pubmed ID | |
Authors |
Derek J. Chong, Andrew M. Lerman |
Abstract |
Since 2010, the Food and Drug Administration has approved the use of four new anti-epilepsy drugs (AEDs) for the treatment of epilepsy in the USA: clobazam (Onfi), ezogabine (Potiga), perampanel (Fycompa), and eslicarbazepine (Aptiom) as well as two extended release formulations, topiramate ER (Qudexy XR and Trokendi) and oxcarbazepine ER (Oxtellar). This not only provides practitioners ample choice to match medication profiles to their patients' preferences and co-morbidities better, but also challenges us to be proficient in the use of all. In addition to providing a brief overview of these new medications and of the current medical management of epilepsy, this review discusses new data regarding vitamin D and AED-related osteoporosis, pregnancy registries, suicidality, marijuana-related compounds for epilepsy, and the recently published guidelines on the approach and management of a first unprovoked seizure in adults and guidelines for when to stop AEDs. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 145 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Bachelor | 22 | 15% |
Student > Master | 17 | 12% |
Other | 16 | 11% |
Student > Ph. D. Student | 13 | 9% |
Student > Doctoral Student | 12 | 8% |
Other | 28 | 19% |
Unknown | 37 | 26% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 47 | 32% |
Pharmacology, Toxicology and Pharmaceutical Science | 16 | 11% |
Neuroscience | 12 | 8% |
Chemistry | 7 | 5% |
Biochemistry, Genetics and Molecular Biology | 6 | 4% |
Other | 17 | 12% |
Unknown | 40 | 28% |