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Automated eligibility screening and monitoring for genotype-driven precision oncology trials

Overview of attention for article published in Journal of the American Medical Informatics Association, March 2016
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Title
Automated eligibility screening and monitoring for genotype-driven precision oncology trials
Published in
Journal of the American Medical Informatics Association, March 2016
DOI 10.1093/jamia/ocw020
Pubmed ID
Authors

Michael H Eubank, David M Hyman, Amritha D Kanakamedala, Stuart M Gardos, Jonathan M Wills, Peter D Stetson

Abstract

The Information Systems Department at Memorial Sloan Kettering Cancer Center developed the DARWIN Cohort Management System (DCMS). The DCMS identifies and tracks cohorts of patients based on genotypic and clinical data. It assists researchers and treating physicians in enrolling patients to genotype-matched IRB-approved clinical trials. The DCMS sends automated, actionable, and secure email notifications to users with information about eligible or enrolled patients before their upcoming appointments. The system also captures investigators input via annotations on patient eligibility and preferences on future status updates. As of August 2015, the DCMS is tracking 159,893 patients on both clinical operations and research cohorts. 134 research cohorts have been established and track 64,473 patients. 51,192 of these have had one or more genomic tests including MSK-IMPACT, comprising the pool eligible for genotype-matched studies. This paper describes the design and evolution of this Informatics solution.

X Demographics

X Demographics

The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 36 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 36 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 10 28%
Student > Ph. D. Student 5 14%
Professor > Associate Professor 4 11%
Student > Doctoral Student 2 6%
Student > Postgraduate 2 6%
Other 5 14%
Unknown 8 22%
Readers by discipline Count As %
Medicine and Dentistry 10 28%
Agricultural and Biological Sciences 6 17%
Biochemistry, Genetics and Molecular Biology 3 8%
Computer Science 2 6%
Business, Management and Accounting 1 3%
Other 4 11%
Unknown 10 28%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 30 March 2017.
All research outputs
#16,046,765
of 25,373,627 outputs
Outputs from Journal of the American Medical Informatics Association
#2,656
of 3,301 outputs
Outputs of similar age
#172,210
of 314,728 outputs
Outputs of similar age from Journal of the American Medical Informatics Association
#55
of 68 outputs
Altmetric has tracked 25,373,627 research outputs across all sources so far. This one is in the 34th percentile – i.e., 34% of other outputs scored the same or lower than it.
So far Altmetric has tracked 3,301 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 14.8. This one is in the 17th percentile – i.e., 17% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 314,728 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 42nd percentile – i.e., 42% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 68 others from the same source and published within six weeks on either side of this one. This one is in the 19th percentile – i.e., 19% of its contemporaries scored the same or lower than it.