| Title |
Psychometric Study of the Aberrant Behavior Checklist in Fragile X Syndrome and Implications for Targeted Treatment
|
|---|---|
| Published in |
Journal of Autism and Developmental Disorders, October 2011
|
| DOI | 10.1007/s10803-011-1370-2 |
| Pubmed ID | |
| Authors |
Stephanie M. Sansone, Keith F. Widaman, Scott S. Hall, Allan L. Reiss, Amy Lightbody, Walter E. Kaufmann, Elizabeth Berry-Kravis, Ave Lachiewicz, Elaine C. Brown, David Hessl |
| Abstract |
Animal studies elucidating the neurobiology of fragile X syndrome (FXS) have led to multiple controlled trials in humans, with the Aberrant Behavior Checklist-Community (ABC-C) commonly adopted as a primary outcome measure. A multi-site collaboration examined the psychometric properties of the ABC-C in 630 individuals (ages 3-25) with FXS using exploratory and confirmatory factor analysis. Results support a six-factor structure, with one factor unchanged (Inappropriate Speech), four modified (Irritability, Hyperactivity, Lethargy/Withdrawal, and Stereotypy), and a new Social Avoidance factor. A comparison with ABC-C data from individuals with general intellectual disability and a list of commonly endorsed items are also reported. Reformulated ABC-C scores based on this FXS-specific factor structure may provide added outcome measure specificity and sensitivity in FXS clinical trials. |
X Demographics
The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 50% |
| Unknown | 1 | 50% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 2 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 141 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 141 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 25 | 18% |
| Student > Ph. D. Student | 18 | 13% |
| Student > Master | 16 | 11% |
| Other | 13 | 9% |
| Student > Bachelor | 9 | 6% |
| Other | 28 | 20% |
| Unknown | 32 | 23% |
| Readers by discipline | Count | As % |
|---|---|---|
| Psychology | 34 | 24% |
| Medicine and Dentistry | 26 | 18% |
| Agricultural and Biological Sciences | 10 | 7% |
| Neuroscience | 9 | 6% |
| Social Sciences | 7 | 5% |
| Other | 19 | 13% |
| Unknown | 36 | 26% |
Attention Score in Context
This research output has an Altmetric Attention Score of 16. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 07 November 2023.
All research outputs
#2,073,077
of 23,867,274 outputs
Outputs from Journal of Autism and Developmental Disorders
#915
of 5,240 outputs
Outputs of similar age
#10,288
of 135,455 outputs
Outputs of similar age from Journal of Autism and Developmental Disorders
#6
of 33 outputs
Altmetric has tracked 23,867,274 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 91st percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 5,240 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 13.2. This one has done well, scoring higher than 83% of its peers.
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We're also able to compare this research output to 33 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 81% of its contemporaries.