Title |
Pioglitazone in Clinical Practice: Where Are We Now?
|
---|---|
Published in |
Diabetes Therapy, February 2012
|
DOI | 10.1007/s13300-012-0001-z |
Pubmed ID | |
Authors |
Joytish Govindan, Marc Evans |
Abstract |
Pioglitazone, a thiazolidinedione, improves insulin sensitivity and thus reduces blood glucose. Clinical trials have suggested potential cardiovascular outcome benefits in association with pioglitazone; however, safety concerns are mounting, with recent data suggesting a link between pioglitazone and an increased risk of bladder cancer. There is thus a growing focus on the risk-benefit profile of this agent and hence its potential role in the blood glucose-lowering treatment algorithm for people with type 2 diabetes. There are clear potential outcome benefits associated with pioglitazone. In this review, the authors focus on putting the true risk-benefit profile of pioglitazone into context based on critical appraisal of the currently available evidence. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Unknown | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Science communicators (journalists, bloggers, editors) | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Unknown | 25 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Bachelor | 5 | 20% |
Professor > Associate Professor | 4 | 16% |
Student > Master | 3 | 12% |
Student > Doctoral Student | 2 | 8% |
Student > Postgraduate | 2 | 8% |
Other | 3 | 12% |
Unknown | 6 | 24% |
Readers by discipline | Count | As % |
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Medicine and Dentistry | 11 | 44% |
Pharmacology, Toxicology and Pharmaceutical Science | 2 | 8% |
Biochemistry, Genetics and Molecular Biology | 1 | 4% |
Environmental Science | 1 | 4% |
Agricultural and Biological Sciences | 1 | 4% |
Other | 1 | 4% |
Unknown | 8 | 32% |