| Title |
Risk of epilepsy in type 1 diabetes mellitus: a population-based cohort study
|
|---|---|
| Published in |
Diabetologia, March 2016
|
| DOI | 10.1007/s00125-016-3929-0 |
| Pubmed ID | |
| Authors |
I-Ching Chou, Chung-Hsing Wang, Wei-De Lin, Fuu-Jen Tsai, Che-Chen Lin, Chia-Hung Kao |
| Abstract |
Type 1 diabetes mellitus is a major public health problem of increasing global concern, with potential neurological complications. A possible association exists between type 1 diabetes and subsequent epilepsy. This study evaluated the relationship between type 1 diabetes and epilepsy in Taiwan. Claims data from the Taiwan National Health Insurance Research Database were used to conduct retrospective cohort analyses. The study cohort contained 2568 patients with type 1 diabetes, each of whom was frequency-matched by sex, urbanisation of residence area and index year with ten patients without type 1 diabetes. Cox proportional hazard regression analysis was conducted to estimate the effects of type 1 diabetes on epilepsy risk. In patients with type 1 diabetes, the risk of developing epilepsy was significantly higher than that in patients without type 1 diabetes (p < 0.0001 for logrank test). After adjustment for potential confounders, the type 1 diabetes cohort was 2.84 times as likely to develop epilepsy than the control cohort was (HR 2.84 [95% CI 2.11, 3.83]). Patients with type 1 diabetes are at an increased risk of developing epilepsy. Metabolic abnormalities of type 1 diabetes, such as hyperglycaemia and hypoglycaemia, may have a damaging effect on the central nervous system and be associated with significant long-term neurological sequelae. The causative factors between type 1 diabetes and the increased risk of epilepsy require further investigation. |
X Demographics
The data shown below were collected from the profiles of 24 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Saudi Arabia | 5 | 21% |
| United States | 3 | 13% |
| Russia | 3 | 13% |
| United Kingdom | 1 | 4% |
| India | 1 | 4% |
| Germany | 1 | 4% |
| Unknown | 10 | 42% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 17 | 71% |
| Practitioners (doctors, other healthcare professionals) | 4 | 17% |
| Scientists | 3 | 13% |
Mendeley readers
The data shown below were compiled from readership statistics for 77 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Canada | 1 | 1% |
| Unknown | 76 | 99% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 12 | 16% |
| Student > Bachelor | 11 | 14% |
| Student > Master | 8 | 10% |
| Researcher | 7 | 9% |
| Student > Doctoral Student | 5 | 6% |
| Other | 19 | 25% |
| Unknown | 15 | 19% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 26 | 34% |
| Pharmacology, Toxicology and Pharmaceutical Science | 7 | 9% |
| Nursing and Health Professions | 6 | 8% |
| Neuroscience | 3 | 4% |
| Agricultural and Biological Sciences | 2 | 3% |
| Other | 8 | 10% |
| Unknown | 25 | 32% |
Attention Score in Context
This research output has an Altmetric Attention Score of 57. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 15 August 2017.
All research outputs
#756,775
of 25,756,911 outputs
Outputs from Diabetologia
#392
of 5,378 outputs
Outputs of similar age
#13,379
of 316,288 outputs
Outputs of similar age from Diabetologia
#6
of 84 outputs
Altmetric has tracked 25,756,911 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 97th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 5,378 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 24.2. This one has done particularly well, scoring higher than 92% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 316,288 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 95% of its contemporaries.
We're also able to compare this research output to 84 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 92% of its contemporaries.