Title |
Mouse-adapted scrapie strains 139A and ME7 overcome species barrier to induce experimental scrapie in hamsters and changed their pathogenic features
|
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Published in |
Virology Journal, March 2012
|
DOI | 10.1186/1743-422x-9-63 |
Pubmed ID | |
Authors |
Qi Shi, Bao-Yun Zhang, Chen Gao, Jin Zhang, Hui-Ying Jiang, Cao Chen, Jun Han, Xiao-Ping Dong |
Abstract |
Transmissible spongiform encephalopathy (TSE) diseases are known to be zoonotic diseases that can infect different kinds of animals. The transmissibility of TSE, like that of other infectious diseases, shows marked species barrier, either being unable to infect heterologous species or difficult to form transmission experimentally. The similarity of the amino acid sequences of PrP among species is believed to be one of the elements in controlling the transmission TSE interspecies. Other factors, such as prion strains and host's microenvironment, may also participate in the process. |
Mendeley readers
The data shown below were compiled from readership statistics for 22 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 22 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 6 | 27% |
Student > Ph. D. Student | 5 | 23% |
Unspecified | 3 | 14% |
Student > Bachelor | 2 | 9% |
Professor | 1 | 5% |
Other | 2 | 9% |
Unknown | 3 | 14% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 5 | 23% |
Biochemistry, Genetics and Molecular Biology | 4 | 18% |
Unspecified | 3 | 14% |
Medicine and Dentistry | 2 | 9% |
Neuroscience | 2 | 9% |
Other | 3 | 14% |
Unknown | 3 | 14% |