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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Δ9‐Tetrahydrocannabinol induces apoptosis in C6 glioma cells
|
|---|---|
| Published in |
Febs Letters, October 1998
|
| DOI | 10.1016/s0014-5793(98)01085-0 |
| Pubmed ID | |
| Authors |
Cristina Sánchez, Ismael Galve-Roperh, Cecile Canova, Philippe Brachet, Manuel Guzmán |
| Abstract |
delta9-Tetrahydrocannabinol (THC), the major active component of marijuana, induced apoptosis in C6.9 glioma cells, as determined by DNA fragmentation and loss of plasma membrane asymmetry. THC stimulated sphingomyelin hydrolysis in C6.9 glioma cells. THC and N-acetylsphingosine, a cell-permeable ceramide analog, induced apoptosis in several transformed neural cells but not in primary astrocytes or neurons. Although glioma C6.9 cells expressed the CBI cannabinoid receptor, neither THC-induced apoptosis nor THC-induced sphingomyelin breakdown were prevented by SR141716, a specific antagonist of that receptor. Results thus show that THC-induced apoptosis in glioma C6.9 cells may rely on a CBI receptor-independent stimulation of sphingomyelin breakdown. |
X Demographics
The data shown below were collected from the profiles of 28 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 5 | 18% |
| Canada | 2 | 7% |
| Korea, Republic of | 2 | 7% |
| Austria | 1 | 4% |
| Korea, Democratic People's Republic of | 1 | 4% |
| United Kingdom | 1 | 4% |
| Chile | 1 | 4% |
| Unknown | 15 | 54% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 28 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 131 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 3 | 2% |
| Spain | 1 | <1% |
| Canada | 1 | <1% |
| Unknown | 126 | 96% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 30 | 23% |
| Researcher | 23 | 18% |
| Student > Master | 16 | 12% |
| Student > Bachelor | 16 | 12% |
| Student > Doctoral Student | 7 | 5% |
| Other | 24 | 18% |
| Unknown | 15 | 11% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 25 | 19% |
| Agricultural and Biological Sciences | 24 | 18% |
| Medicine and Dentistry | 15 | 11% |
| Neuroscience | 10 | 8% |
| Pharmacology, Toxicology and Pharmaceutical Science | 9 | 7% |
| Other | 24 | 18% |
| Unknown | 24 | 18% |
Attention Score in Context
This research output has an Altmetric Attention Score of 204. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 18 October 2023.
All research outputs
#191,997
of 25,374,647 outputs
Outputs from Febs Letters
#6
of 14,373 outputs
Outputs of similar age
#41
of 34,233 outputs
Outputs of similar age from Febs Letters
#1
of 155 outputs
Altmetric has tracked 25,374,647 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 99th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 14,373 research outputs from this source. They receive a mean Attention Score of 4.7. This one has done particularly well, scoring higher than 99% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 34,233 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 99% of its contemporaries.
We're also able to compare this research output to 155 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 99% of its contemporaries.