Title |
A toy model of fractal glioma development under RF electric field treatment
|
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Published in |
The European Physical Journal E, June 2012
|
DOI | 10.1140/epje/i2012-12042-9 |
Pubmed ID | |
Authors |
A. Iomin |
Abstract |
A toy model for glioma treatment by a radio frequency electric field is suggested. This low-intensity, intermediate-frequency alternating electric field is known as the tumor-treating field (TTF). In the framework of this model the efficiency of this TTF is estimated, and the interplay between the TTF and the migration-proliferation dichotomy of cancer cells is considered. The model is based on a modification of a comb model for cancer cells, where the migration-proliferation dichotomy becomes naturally apparent. Considering glioma cancer as a fractal dielectric composite of cancer cells and normal tissue cells, a new effective mechanism of glioma treatment is suggested in the form of a giant enhancement of the TTF. This leads to the irreversible electroporation that may be an effective non-invasive method of treating brain cancer. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Israel | 1 | 3% |
Unknown | 30 | 97% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 5 | 16% |
Student > Doctoral Student | 4 | 13% |
Student > Master | 4 | 13% |
Student > Bachelor | 2 | 6% |
Professor | 2 | 6% |
Other | 6 | 19% |
Unknown | 8 | 26% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 8 | 26% |
Agricultural and Biological Sciences | 6 | 19% |
Physics and Astronomy | 3 | 10% |
Neuroscience | 2 | 6% |
Biochemistry, Genetics and Molecular Biology | 1 | 3% |
Other | 2 | 6% |
Unknown | 9 | 29% |